FNDC5 genetic polymorphism in patients with peripartum cardiomyopathy.

Background: Late in pregnancy or soon after delivery, peripartum cardiomyopathy (PPCM) which is an uncommon type of cardiomyopathy, can develop. To assess the association between the level of irisin expression and (FNDC5) (rs3480) gene polymorphism with peripartum cardiomyopathy.

Methods: This is a case control study included a thirty female patients with new-onset PPCM and sixty healthy females at the at the peripartum period in same time window for PPCM as a control.

Irisin expression and (rs3480) gene polymorphism in type 2 diabetic patients with and without CAD.

Background: Irisin was found to correlate with coronary artery disease (CAD) in diabetic patients. This study investigated the association of irisin and (SNP rs3480) with the presence and severity of CAD in T2DM.

Methods: This cross-sectional study included 100 patients with T2DM divided into two groups, DM group ( = 50), including patients without CAD and CAD group ( = 50), including those confirmed to have CAD by coronary angiography.