Effect of salt loading on baroreflex sensitivity in reduced renal mass hypertension.

Background: High dietary salt, as well as renal mass reduction, is known to decrease baroreflex sensitivity in rats. However, the effect of high salt intake on baroreflex sensitivity is unknown in reduced renal mass (RRM) hypertension; therefore, the aim of this study was to investigate the effects of salt loading on arterial baroreflex sensitivity and mean arterial pressure (MAP) in RRM hypertension.

Methods: Both RRM and sham-operated control (SO) rats were loaded with 0.