Antibiotics for Periodontal Infections: Biological and Clinical Perspectives.

Aim: The review is to highlight the use of antibiotics in periodontal infections and prevent indiscriminate use of antibiotics.

Background: Periodontitis is the most common disease of the periodontal attachment apparatus, and its etiological factor can be related to the existence of virulent microorganisms in the dental plaque biofilm which harbors millions of microorganisms. In addition, the pathogenesis of this disease is greatly influenced by the host immune response that leads to the cyclic destruction and healing pattern.