Publications by authors named "Ali M Mohammed"

Fournier's gangrene is a grave necrotizing fasciitis that primarily affects the perineum, spreading through the fascias and leading to significant tissue destruction. The involvement of the urethra in necrosis is extremely rare, if not anecdotal. Emphysematous pyelonephritis, is a urinary infection with a high risk of progression to sepsis.

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Background: Metallo-beta lactamase resistance is one of the carbapenem resistances that worsen the world nowadays. A new variant of carbapenem-resistant has only limited reports from Africa including Ethiopia. This study aimed to determine Metallo -ß- lactamase resistance Gram-negative bacteria in Hawassa University Comprehensive Specialized Hospital January-June 2023.

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Fetal complications can occur if pregnant women with urinary tract infection (UTI) are not treated. We aimed to determine the magnitude of UTI, drug resistance profile, and fetal outcomes among pregnant women in Adare General Hospital, Hawassa, Ethiopia. Facility-based cross-sectional study was conducted among 308 pregnant women using questionnaire and review of medical records.

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  • * Significant risk factors associated with S. Typhi infection include not washing hands before meals, eating raw vegetables, and drinking stream water, indicating potential prevention measures.
  • * The bacteria showed high susceptibility to antibiotics with 90% effective response to ciprofloxacin, and 80% efficacy to ceftriaxone and chloramphenicol, suggesting these treatments could be effective choices for managing infections.
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  • The study investigates the prevalence of rectovaginal group B Streptococcus (GBS) colonization in pregnant women during labor and its transmission to newborns in selected low-income and middle-income African and South Asian countries.
  • Conducted across 11 maternity and obstetric facilities, the research involved collecting samples from 6,514 HIV-negative pregnant women at least 37 weeks gestation to analyze GBS culture and serotyping.
  • The findings revealed a 24.1% rate of maternal GBS colonization, with the highest prevalence in Mali (41.1%) and the lowest in Ethiopia (11.6%), highlighting significant regional variations in GBS rates among pregnant women.
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Background: Meningitis poses a significant challenge to public health in low-income nations, such as Ethiopia, with a particular impact on newborns. The magnitude and etiologies of meningitis vary based on geographic location and age of patients. There is limited data regarding the magnitude and etiology of meningitis from Sidama Regional State, Ethiopia.

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Asymptomatic malaria can impact existing malaria control and elimination efforts around the world, particularly in Africa, where the majority of malaria cases and death occurs. This is a cross-sectional study aimed to determine the prevalence and predictors of asymptomatic malaria among migrant farmworkers from June to July 2020 in the Upper Awash Agro-industry, East Shewa zone, Oromia Regional State, Ethiopia. A total of 254 migrant farmworkers without signs and symptoms of malaria were enrolled.

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Introduction: Proper diagnosis of tuberculosis (TB) lymphadenitis is critical for its treatment and prevention. Fine needle aspirate cytology (FNAC) is the mainstay method for the diagnosis of TB lymphadenitis in Ethiopia; however, the performance of FNAC has not been evaluated in the Eastern Region of Ethiopia. This study aimed to evaluate the performance of FNAC and Ziehl-Neelsen (ZN) staining compared with that of GeneXpert for the diagnosis of TB lymphadenitis.

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Background: Coliform, , and are among the most encountered bacteria in raw milk. This study is aimed at determining the extent of coliform, , and in raw milk and vendor hygiene practices at Asella town, Oromia Regional State, Ethiopia, from March 1 to 30, 2022.

Methods: In this study, 210 milk vendors were included; each vendor provided a 50 ml sample of raw milk.

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Unlabelled: Gastroesophageal reflux disease (GERD) is a common upper gastrointestinal disorder characterized by troublesome symptoms, including heartburn and acid regurgitation. GERD is associated with complications such as peptic stricture, Barrett's esophagus, and esophageal adenocarcinoma, and it negatively affects quality of life (QoL).

Aims: To assess the factors influencing the QoL of GERD patients in the Aseer region of Saudi Arabia.

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  • * Researchers analyzed 40 articles with a total of 12,239 human specimens, finding that 545 isolates (about 72%) were multidrug-resistant, with prevalence rates varying widely between studies.
  • * The study used various statistical methods and tools to assess the quality of the articles and the robustness of the findings, identifying Addis Ababa as having a particularly high prevalence of MDR Klebsiella at 97%.
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  • The study focuses on the global health issue of vancomycin-resistant Enterococci (VRE), which poses a risk for healthcare-associated infections in vulnerable hospitalized patients.
  • Conducted at Hawassa University Comprehensive Specialized Hospital, the research involved analyzing stool samples from 223 patients over a three-month period to determine the prevalence and factors associated with VRE colonization.
  • Results indicated a gastrointestinal colonization rate of 6.7% for VRE, with significant associations found for patients with no formal education, those hospitalized for over two weeks, and those with a history of vancomycin treatment.
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Objectives: To compare the outcomes of bipolar Transurethral Enucleation Resection of the Prostate (TUERP) and simple retropubic prostatectomy in patients with prostate volumes larger than 80 cc.

Patients And Methods: A prospective randomized study included all patients amenable to surgeries for benign prostate hyperplasia (BPH) with prostate size over 80 cc at a tertiary care hospital between January 2020 to February 2022. Bipolar TUERP and Retropubic open prostatectomy techniques were compared regarding patients' demographics, intraoperative parameters, outcomes, and peri-operative complications.

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Mycobacterium tuberculosis complex has an impact on public health and is responsible for over one million deaths per year. Substantial numbers of people infected with M. tuberculosis can develop tuberculosis lymphadenitis; however, there is a limited study in Adama, Ethiopia.

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Background: Podoconiosis is one of the neglected tropical diseases (NTD) with the greatest potential for elimination. Despite its public health importance, podoconiosis is a poorly understood disease which led to a widespread misconception about its cause, prevention, and treatment. Even though the exact global burden is still to be measured, it is estimated that at least 4 million people are affected with podoconiosis worldwide, of which more than 1.

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Background: In patients with type 2 diabetes mellitus, the development of diabetic retinopathy (DR) correlates positively with elevated serum chemerin levels. This study was aimed at investigating the probable association between the serum chemerin level and the development of DR in patients with type 1 diabetes mellitus (T1DM).

Methods: In this cross-sectional study, we included Egyptians and classified them into four groups: group 1, including healthy individuals; group 2, including patients with T1DM without DR; group 3, including patients with T1DM with non-proliferative DR (NPDR); and group 4, including patients with T1DM with proliferative DR (PDR).

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Canines historically have been proven to have great benefits in human medicine. They have a unique ability to detect volatile organic compounds, or VOCs, in several different diseases, which allows them to work efficiently as a medical alert dog or detect the presence of certain diseases in human samples. Early studies have shown efficiency in the ability of canines to detect malignant cells from primary lung tumors in the fluid and breath samples of patients.

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Background: Worldwide, more than one million peoples acquire sexually transmitted infections (STIs). The burden of STIs and the youth awareness level on the transmission of STIs is under investigated in Sidama Regional State.

Objective: To determine the seroprevalence of STIs such as hepatitis B surface antigen (HBsAg), Anti-hepatitis C virus (HCV) antibodies, Human Immunodeficiency virus (HIV) seroprevalence, and syphilis and to determine associated factors among youth-friendly services Attendees at selected health facilities in Hawassa city, Ethiopia.

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  • This study evaluated how well Fine Needle Aspiration Cytology (FNAC) diagnoses lymph node issues compared to Histopathologic examination.* -
  • Conducted on 101 patients in Hawassa city from 2016 to 2021, the study found FNAC was fairly accurate, with a sensitivity of 88.2% and specificity of 92% for diagnosing lymphoma.* -
  • Researchers recommend FNAC as a first-line diagnostic test for significant lymphadenopathy due to its speed, safety, cost-effectiveness, and good predictive values.*
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Neonatal sepsis is a systemic infection that occurs at an early age. Its etiology varies from one region to the other. The contribution of sepsis to neonatal mortality and morbidity is significant in resource-limited countries; however, there is limited information about the etiology of sepsis in Sidama Regional State, Ethiopia.

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  • - The study investigates the prevalence and antibiotic resistance of Streptococcus infection among adult patients suspected of having tuberculosis at Dilla University Referral Hospital in Ethiopia, finding a 21.4% prevalence rate.
  • - A significant level of antibiotic resistance was observed, with high rates of resistance to penicillin (74.1%) and tetracycline (78.7%), and 46.1% of the bacterial isolates showed multidrug resistance.
  • - Factors such as lower educational status, larger family size, and living in crowded conditions were associated with an increased likelihood of Streptococcus infection among the participants.
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: Bacterial contamination of medical equipment, inanimate surfaces, and indoor air of the hospital environment is the main source of hospital-acquired infection in developing countries. : The aim of this study was to determine the bacterial contamination rates for medical equipment, inanimate surfaces, and indoor air, and the drug susceptibility profiles of bacteria, in the neonatal intensive care unit and pediatric ward of Hawassa University Comprehensive Specialized Hospital (HUCSH). A hospital-based cross-sectional study was carried out from October 20 to December 30, 2020.

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Introduction: Methicillin-resistant (MRSA) is a major cause of hospital-acquired infection, which is difficult to treat because of antibiotic resistance. There is scant data on MRSA from southern parts of Ethiopia.

Objective: The aim of this study was to determine the prevalence of MRSA nasal carriage, antibiotic susceptibility profiles, and associated factors among hospitalized patients attending Hawassa University Comprehensive Specialized Hospital (HUCSH), Hawassa, Ethiopia.

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Background: HIV is among one of the most serious public health problems. Low-income countries are highly affected by Human Immuno-deficiency Virus (HIV). The burden of HIV varies across various segments of the population.

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