Correlation of Sperm Mitochondrial DNA 7345 and 7599 Deletions with Asthenozoospermia in Jordanian Population.

Background: Alterations in sperm mitochondrial DNA (mtDNA) affect the functions of some OXPHOS proteins which will affect sperm motility and may be associated with asthenozoospermia. The purpose of this study was to investigate the correlation between 7599- and 7345- sperm mtDNA deletions and asthenozoospermia in Jordan.

Methods: Semen specimens from 200 men including 121 infertile and 79 healthy individuals were collected at the Royal Jordanian Medical Services In-vitro fertilization (IVF) units.