Publications by authors named "Ali Karimi Akhormeh"

Article Synopsis
  • The study examined the link between stent sizes and clinical outcomes in diabetic patients after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) and dual antiplatelet therapy (DAPT).
  • Out of 1630 patients, 29% had diabetes, but there was no significant difference in major adverse cardiac events (MACE) between diabetic and nondiabetic patients, despite stent size differences.
  • The findings suggest that diabetes did not affect MACE rates, and stent size was not significantly associated with outcomes in diabetics, emphasizing the importance of long-term DAPT and glycemic control post-PCI.
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Background: Left ventricular hypertrophy (LVH) is a common diagnosis in patients with cardiovascular disease (CVD). The prevalence of LVH among patients with Type-2 Diabetes Mellitus (T2DM), high blood pressure and aging is higher than the healthy population and has been independently associated with an increased risk for future cardiac event, including stroke. The aim of this study is to identify the prevalence of LVH among T2DM subjects and evaluate its association with related risk factors of CVD patients in the metropolis of Shiraz, Iran.

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The case report presented is a 22-year-old female with an undiagnosed nasal foreign body (NFB) in her right nasal cavity for 18 years. Previous physical examination and anterior rhinoscopy by other health care specialists failed to detect the NFB. She was treated conservatively by many ENT specialists as sinusitis with antibiotics therapy and anti-allergy drugs for many years with no improvement.

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Coronary artery disease has remained a major health challenge despite enormous progress in prevention, diagnosis, and treatment strategies. Formation of atherosclerotic plaque is a chronic process that is developmentally influenced by intrinsic and extrinsic determinants. Inflammation triggers atherosclerosis, and the fundamental element of inflammation is the immune system.

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There is a huge number of noncoding RNA (ncRNA) transcripts in the cell with important roles in modulation of different mechanisms. ANRIL is a long ncRNA with 3.8 kb length that is transcribed in the opposite direction of the INK4/ARF locus in chromosome 9p21.

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Article Synopsis
  • - The study aimed to evaluate four different definitions of metabolic syndrome (Mets) to see how well they predict participants' 10-year cardiovascular disease risk using data from the Shiraz Heart Study in Iran.
  • - A total of 7,225 participants were analyzed, with the majority being male and an average age of 52 years; results indicated that the WHO definition identified the fewest cases of Mets but showed significant risk score differences for AHA, WHO, and NCEP ATP III.
  • - The findings concluded that the International Diabetes Federation (IDF) definition was ineffective for distinguishing between those with Mets and their cardiovascular risk, unlike the other three definitions, which showed significant risk differences.
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Atherosclerotic lesions of the coronary arteries are still in charge of significant annual morbidity and mortality despite intense therapeutic advancements. Genome-born elements contribute substantially to the atherosclerosis process. ANRIL is one of the long non-coding RNAs with outstanding functions particularly regulation of genes involved in atherosclerosis development.

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CD4 + T-lymphocyte counts are used to assess CD4 + decline and the stage of human immunodeficiency virus (HIV) progression in HIV-infected patients. Clinical observation suggests that HIV progress more rapid in females than males. Of the original 5000 HIV-infected population of Western New York HIV/AIDS, Referral Center at Erie County Medical Center (ECMC), 1422 participated in the cohort study.

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To determine the conclusive integrity in the Shiraz Cohort Heart Study (SCHS) project, management began quality assurance (QA) and quality control (QC) of the collected data throughout the study end-points. The QA is a focused process that prevents and detects data collection errors and verification of intended requirements in the SCHS. The QC is a subset of QA intended to capture errors in processing data through testing and preventive processes to identify problems, defects, or intended requirements.

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