Effectiveness of human adipose tissue-derived mesenchymal stem cells expressing alpha-1 antitrypsin gene in liver fibrosis: a study in mice.

Aim: The present study examined the protective potential of human adipose tissue-derived mesenchymal stem cells (hASCs) modified to overexpress alpha-1 antitrypsin (AAT), in a mouse model of the liver fibrosis.

Background: For the treatment of end-stage liver diseases, cell therapy has emerged as a promising noninvasive alternative to liver transplantation. Mesenchymal stem cells (MSCs) are being evaluated due to their dual capabilities of promoting liver regeneration and modulating the pathogenic inflammation of the immune system.

Improving the Concrete Crack Detection Process via a Hybrid Visual Transformer Algorithm.

Inspections of concrete bridges across the United States represent a significant commitment of resources, given their biannual mandate for many structures. With a notable number of aging bridges, there is an imperative need to enhance the efficiency of these inspections. This study harnessed the power of computer vision to streamline the inspection process.

Investigating the impact of air pollution and temperature changes on emergency admissions (cardiovascular + respiratory) disease in the city of Bojnord, northeastern Iran.

Cardiovascular (CVD) + Respiratory diseases are recognized as the main cause of death worldwide. Fluctuations in temperature and air pollution have been reported as one of the most important causes of cardiovascular & respiratory diseases. Therefore, in the current study, we assessed the relationship between ambient air temperature and pollution on the number of total emergency hospital admission due to cardiovascular and respiratory conditions in the City of Bojnord, northeastern Iran.

Ultrasparse Ultrasonic Synthetic Aperture Focus Imaging by Passive Sensing.

Ultrasonic synthetic aperture focus techniques (SAFTs) using less than the total number of available array elements to transmit ("sparse" transmissions) have been recently used in both medical imaging and industrial nondestructive testing (NDT) imaging to increase test speed and simplify multiplexer hardware. The challenge of sparse arrays is to obtain a reasonable image quality given the reduced transmitter-receiver combinations available to the beamforming process. This article proposes a "ultrasparse" SAFT method that employs a minimum number of transmitter elements (from one to four elements only) to obtain an entire full-matrix capture (FMC) set of waveforms.

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study.

Background: The surge in the utilization of CT scans for COVID-19 diagnosis and monitoring during the pandemic is undeniable. This increase has brought to the forefront concerns about the potential long-term health consequences, especially radiation-induced cancer risk. This study aimed to quantify the potential cancer risk associated with CT scans performed for COVID-19 detection.

Web-Based Information on Spinal Cord Stimulation: Qualitative Assessment of Publicly Accessible Online Resources.

Background: Despite the growing accessibility of web-based information related to spinal cord stimulation (SCS), the content and quality of commonly encountered websites remain unknown.

Objective: This study aimed to assess the content and quality of web-based information on SCS.

Methods: This qualitative study was prospectively registered in Open Science Framework.

The biogas upgrading from landfill leachate pretreated with low-frequency ultrasonic: anaerobic digestion performances and energy balance.

The efficient biogas production from landfill leachate (LL) is one of hot topics in anaerobic digestion systems. Higher bioavailability of LL can be achieved by application a feasible and promising pretreatment technologies in order to utilize as a substrate for anaerobic reactors. Here, the enhanced bioavailabity of LL using the low-frequency ultrasonic process and energy balance in anaerobic digestion process was estimated within incubation period of 24 days.

Relationship between academic success, distance education learning environments, and its related factors among medical sciences students: a cross-sectional study.

Background: Academic success is among the most important criteria for determining students' competence. Hence, one of the concerns of education system researchers has always been investigating its associated factors. Therefore, this study aimed to determine the relationship between academic success, distance education learning environments, and its related factors among Shahroud University of Medical Sciences students.

Antibiotic use and multiple sclerosis: A systematic review and meta-analysis.

Background: Epidemiological studies have shown conflicting results between antibiotic use and multiple sclerosis (MS) risks. The present systematic review and meta-analysis were conducted to assess the association between antibiotic use and the risk of MS.

Methods: PubMed, Scopus, Embase, Web of Science, and Google Scholar as well as reference lists of retrieved studies were searched systematically to identify studies were assessed the relationship between antibiotic use and MS up to September 24, 2022.

Challenges, recent development, and opportunities of smart waste collection: A review.

Population growth and changing consumption patterns make waste management a significant global challenge. Studies evaluated that by 2050 almost 67 % of the Earth's population will live in megacities, which guides the requirement of smart assistance to answer the citizens' demands. Waste collection is an efficient IoT service that takes advantage of cost and energy efficiency.

Railroad Sleeper Condition Monitoring Using Non-Contact in Motion Ultrasonic Ranging and Machine Learning-Based Image Processing.

An ultrasonic sonar-based ranging technique is introduced for measuring full-field railroad crosstie (sleeper) deflections. Tie deflection measurements have numerous applications, such as detecting degrading ballast support conditions and evaluating sleeper or track stiffness. The proposed technique utilizes an array of air-coupled ultrasonic transducers oriented parallel to the tie, capable of "in-motion" contactless inspections.

Concentration of heavy metals in leachate, soil, and plants in Tehran's landfill: Investigation of the effect of landfill age on the intensity of pollution.

Heavy metals are one of the important pollutants in landfill leachate. Plants and soil near the landfill may be contaminated by leachate. In this study, by evaluating the heavy metals in the leachate of two landfills and the soil and plants near them, the amount of pollution caused by the leachate in the environment around the landfills in Tehran was investigated.

No pain, no strain: Targin® mitigates pain and constipation following spinal cord injury.

Background: Opioids effectively reduce chronic pain, but present significant side effects including opioid-induced constipation. Oxycodone/naloxone decreases pain and constipation in cancer patients, however its effect on spinal cord injury population remains understudied.

Methods: We assessed whether oxycodone/naloxone reduces pain, constipation, and severity of autonomic dysreflexia in an individual with spinal cord injury.

Multiple sclerosis incidence temporal trend in the Northeast of Iran: Using the Empirical Bayesian method.

Background: In recent years dramatic changes in multiple sclerosis (MS) incidence have been reported in different provinces in Iran. This study was conducted to assess MS incidence temporal trends from March 21, 2005, to March 20, 2020, and provide a forecast until the end of 2025 in Shahroud county.

Methods: This longitudinal study was carried out based on the data obtained from the MS registration system in Shahroud county.

The prognostic effect of ST-elevation in lead aVR on coronary artery disease, and outcome in acute coronary syndrome patients: a systematic review and meta-analysis.

Background: Rapid diagnosis of coronary artery disease has an important role in saving patients. The aim of this study is to evaluate if aVR lead ST-elevation (STE) can predict LM/3VD, left main (LM) disease, and three-vessel disease (3VD), outcome in acute coronary syndrome (ACS) patients.

Methods: In this systematic review and meta-analysis, 45 qualified studies were entered.

May I Have This Dance: A Case-Series on the Acute Cardiometabolic Demand of Wheelchair Dancing in Recreational Dancers with Spinal Cord Injury.

Objectives: This case-series investigated energy expenditure, cardiovascular responses, and psychosocial outcomes during two wheelchair dancing routines with different tempos.

Methods: Three individuals with chronic, non-traumatic spinal cord injuries [males, mean age 42 (13) years, C3-T12, AIS D, schwannoma=1, poliomyelitis=1, ependymoma=1] performed slow (rumba, 80 bpm) and fast (salsa, 170 bpm) wheelchair dance routines. Physiological [heart rate, blood pressure, relative oxygen consumption (VO2), metabolic task equivalent] and psychosocial parameters [ratings of perceived exertion, enjoyment and Brunel Mood Score] were measured pre, during, and post-dancing.

Development of Streptococcus equisimilis Group G Mutant Strains with Ability to Produce Low Polydisperse and Low-Molecular-Weight Hyaluronic Acid.

Background: Background: Hyaluronic acid (HA), a natural polymer with wide applications in biomedicine and cosmetics, is mainly produced by Streptococcal fermentation at industrial scale. In the present study, chemical random mutagenesis was used for development of Streptococcus equisimilis group G mutant strains with high HA productivity.

Methods: Methods: The optimum of the pH of culture condition and cultivation time for HA production by wild strain group G were assessed.

Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study.

Background: Isolated systolic hypertension (ISH), is the most common form of hypertension in older adults. However, the ISH prevalence is not well known in many developing countries such as Iran. This study was conducted to determine the ISH prevalence and its related risk factors in an Iranian population.

COVID-19 cases, hospitalizations and deaths after vaccination: a cohort event monitoring study, Islamic Republic of Iran.

Objective: To investigate the incidence of coronavirus disease 2019 (COVID-19) cases, hospitalizations and deaths in Iranians vaccinated with either AZD1222 Vaxzevria, CovIran® vaccine, SARS-CoV-2 Vaccine (Vero Cell), Inactivated (lnCoV) or Sputnik V.

Methods: We enrolled individuals 18 years or older receiving their first COVID-19 vaccine dose between April 2021 and January 2022 in seven Iranian cities. Participants completed weekly follow-up surveys for 17 weeks (25 weeks for AZD1222) to report their COVID-19 status and hospitalization.

Risk Factors Associated with Mortality in COVID-19 Patient's: Survival Analysis.

Background: The effect of related factors on recovery or death rates may vary from country to country. Therefore, we aimed to investigate the relationship between demographic, clinical, laboratory factors on the survival rates of confirmed cases of COVID-19 in Shahroud, Iran.

Methods: This is an analytical study of the estimation of the survival of patients with COVID-19.

Cigarette butt littering consequences: a study of pollution rate on beaches and urban environments.

Cigarette butts are hazardous wastes that are not properly discarded by most smokers. They are one of the most abundant litters in the environment and a threat to various organisms because they leak numerous pollutants. This study aimed to assess the distribution of cigarette butts in a coastal city south of the Caspian Sea in Mazandaran Province, Iran.

Epidemiological patterns of syndromic symptoms in suspected patients with COVID-19 in Iran: A Latent Class Analysis.

Background: Early diagnosis and supportive treatments are essential to patients with coronavirus disease 2019 (COVID-19). Therefore, the current study aimed to determine different patterns of syndromic symptoms and sensitivity and specificity of each of them in the diagnosis of COVID-19 in suspected patients.

Study Design: Cross-sectional study .