Publications by authors named "Ali Hassan"

Background: Following the latest war in 2023, over nine million people have been internally displaced, of which White Nile State received over 50,000. They lived in different camps and moved to big cities. This study assessed the scope of mental and physical concerns among the IDPs to identify important healthcare needs.

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The term chondrosarcoma refers to a rare and heterogeneous group of malignant cartilaginous tumors that are typically resistant to chemotherapy and radiotherapy. Metastatic chondrosarcoma has a poor prognosis, and effective systemic therapies are lacking. Isocitrate dehydrogenase (IDH) mutations represent a potential therapeutic target, but IDH inhibitors alone have shown limited clinical efficacy to date.

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Diversification of the cellulose synthase superfamily of glycosyltransferases has provided plants with the ability to synthesise varied cell wall polysaccharides such as xyloglucan, mannans and the mixed-linkage glucans of cereals. Surprisingly, some but not all members of the cellulose synthase-like M (CslM) gene family have recently been shown to be involved in the glycosylation of the aglycone core of a range of triterpenoid saponins. However, no cell wall activity has yet been attributed to any of the CslM gene family members.

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Background: Restoration of a straight and adequately wide nasal dorsum is challenging in patients with deviated noses. Supporting a reformed septum with an extended spreader graft (ESG) is important for maintaining position.

Objective: The study aimed to describe different types of ESG and propose a comprehensive algorithm for using specific types of ESGs in rhinoplasty according to the particular type of deviated nose.

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Background: Obesity is an increasing health concern, affecting 39% of the population. In Qatar, in recent years, the obese population contributed 35.9% of men and 46.

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Article Synopsis
  • Post-error slowing, a phenomenon observed in motor sequence learning tasks, was studied to determine if it depends on extrinsic error feedback.
  • The experiment involved 30 participants who completed a serial reaction time task with and without error feedback, revealing that post-error slowing occurred regardless of feedback presence.
  • While feedback increased the extent of response slowing after errors, it didn't affect overall motor sequence learning, suggesting that feedback primarily helps reduce error rates rather than being essential for understanding motor learning processes.
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Poroma is a relatively rare benign adnexal neoplastic lesion that usually affects elderly patients in the extremities, with an unclear pathogenesis. It is notable for having a variety of morphological appearances that make diagnosis challenging, particularly when observed on an uncommon anatomical site. Here, we present a case of a woman in her mid-50s who presented with a skin pedunculated lesion over the right thigh.

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Introduction: Diabetes causes complications like delayed wound healing for a long time. Fibroin, aloe vera, and ginger extracts along with their combinations are used for diabetic wound healing.

Methods: After induction of diabetes, The wound healing effects of fibroin (50 mg/ml), aloe vera gel (50 mg/ml), and ginger extract (30 mg/ml), individually and in combination, were assessed.

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Diffuse large B cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma and the most frequently diagnosed hematologic malignancy in the United States. DLBCL exhibits significant molecular and clinical heterogeneity, and at least a third of patients are left uncured with standard frontline chemoimmunotherapy. As such, there is a critical need to identify novel targeted therapies to improve outcomes.

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Ribosomal proteins are considered to be involved in the immunity of different animals against pathogens. The protein level of RPL23 increased after fungal infection in termites, but how it influence active immunity in termites is unknown. The role of RPL23 gene was studied to evaluate its impact on active immunity of termite Reticulitermes chinensis against entomopathogenic fungus (EPF) Metarhizium anisopliae.

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Iron oxide nanoparticles, due to their magnetic properties, are versatile tools for biomedical applications serving both diagnostic and therapeutic roles. Their performance is intricately intertwined with their fate in the demanding biological environment. Once inside cells, these nanoparticles can be degraded, implying a loss of magnetic efficacy, but also transformed into neo-synthesized magnetic nanoparticles, potentially restoring functionality.

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Objective: To compare the modulation complexity scores across treatment sites, and to examine their connection with monitor unit, segment number and global and local gamma passing percentage.

Methods: The cross-sectional study was conducted at the Baghdad Centre for Radiation Therapy and Nuclear Medicine, Baghdad Medical City, Baghdad, Iraq, from May 2021 to February 2022. Included were 34 patients, with the age range between 20 - 50 years, subjected to intensity-modulated radiation therapy for head and neck tumours in group A or pelvic tumours in group B.

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The primary aim of the article is to analyze the response of the human immune system when it encounters the hepatitis B virus. This is done using a mathematical system of differential equations. The differential equation system has six components, likely representing various aspects of the immune response or virus dynamics.

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Unlabelled: Extra Nasopharyngeal Angiofibromas are rare benign vascular tumors typically affecting adolescent males. They have variable sites of origin. Only five cases of extra nasopharyngeal angiofibroma originating from the middle turbinate have been reported in the literature, here we present the sixth such case.

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Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease characterized by complex metabolic rewiring that enables growth in changing nutrient availability and oxygen conditions. Transcriptome-based prognostic PDAC tumor subtypes, known as 'basal-like' and 'classical' subtypes are associated with differences in metabolic gene expression including genes involved in glycolysis. Tumor subtype-specific metabolism phenotypes may provide new targets for treatment development in PDAC, but their functional relevance has not been fully elucidated.

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Introduction: Impacted mandibular third molars pose challenges in dental practice, often requiring surgical intervention. This retrospective study aims to analyze the demographics, impaction patterns, and anatomical relationships of impacted mandibular third molars among Saudi patients.

Methodology: Data from 722 patients visiting the Department of Maxillofacial Surgery and Diagnostic Sciences at Jizan University were retrospectively analyzed.

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A significant share of wastewater produced during different processes is released to the surroundings without further treatment. Therefore, polluted water sources are triggering diseases like typhoid. To avoid this, various techniques have been developed for the removal of contaminants from the water.

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The pollution of wastewater with pharmaceuticals and endocrine-disrupting chemicals (EDCs) in populated areas poses a growing threat to humans and ecosystems. To address this serious problem, various one-dimensional (1D) hierarchical ZnO-based nanostructures inspired by Anelosimus eximius cobwebs were developed and successfully grown on a glass substrate through simple hydrothermal synthesis. The nanorods (nr) obtained during primary growth were chemically etched with KOH (ZnO-KOH), followed by the secondary growth of nano cobweb-like (ncw) structures using polyethyleneimine (ZnO).

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Coronary artery disease (CAD) is one of the most common causes of sudden cardiac arrest, accounting for a large percentage of global mortality. A timely diagnosis and detection may save a person's life. The research suggests a methodological framework for non-invasive risk stratification based on information only possible after invasive coronary angiography.

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Background: The relationship between the microbiome and oral health is intricate, yet there is a lack of comprehensive knowledge regarding the microbiome's impact on oral health. Integrating knowledge regarding the oral microbiome and its significance in oral and systemic diseases holds profound implications for dental professionals in patient care and professional development. This study assessed dental professionals' oral microbiome comprehension and knowledge levels in Saudi Arabia and its implications for oral healthcare.

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Dromedary camels can survive and reproduce in desert areas. The unique anatomical structure of the kidney enables the camel to prevent water loss. The present study aimed to investigate the ultrastructure of the peroxisomes in the normal kidney of the adult dromedary camel.

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Diabetes mellitus causes impaired diabetic wounds which is linked to a number of pathological alterations that impede the healing of wounds. In the current research, Swiss albino mice were given alloxan monohydrate to induce diabetes and excision wounds of approximately 6 mm using biopsy punch. The diabetic wounds were treated with various biomaterials including Vachellia nilotica extract (VN), Nigella sativa extract (NS), V.

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Synopsis of recent research by authors named "Ali Hassan"

  • - Ali Hassan's recent research spans various fields, including diabetic wound healing, oncology, entomology, and biomedical engineering, demonstrating a strong interdisciplinary approach to addressing health-related challenges.
  • - Key findings include the potential of fibroin, aloe vera, and ginger extracts for improving diabetic wound healing, as well as the identification of GAK as a novel therapeutic target in diffuse large B-cell lymphoma, highlighting the importance of novel treatment strategies in cancer care.
  • - Additional investigations include the role of the RPL23 gene in termite immunity, the dynamics of biodegradation in human stem cells, and the synthesis of reduced graphene oxide for environmental remediation, showcasing Hassan's contributions to both biological and environmental sciences.