The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.

Background: Breast cancer is one of the most common diseases globally that may have side effects on liver and renal function. Pharmacological treatments to reduce adverse liver and renal effects are still limited. It has been proposed that silymarin may possess hepatoprotective and anti-inflammatory properties.

Complementary and Alternative Medicine in Cancer Patients and the Causes of Tendency to Use Such Treatments in Isfahan, Iran.

Background And Aim: The current study aimed to, first, investigate the frequency of cancer patients who receive complementary and alternative medicine (CAM), separated by the type of the disease, and second, to study their incentives and causes of use.

Materials And Methods: Following a cross-sectional design, cancer cases referred to referral centers of cancer in Isfahan province were studied. Data were collected using a researcher-developed checklist that included type of the disease, complementary medicine, and causes of a tendency to use CAM.

Evaluation of Sleep Training Effectiveness on the Quality of Sleep in Cancer Patients during Chemotherapy.

Background: Sleep disorder is one of the most common problems in cancer patients involved in chemotherapy stages, which is caused by the side effects of anticancer drugs and the exacerbation of mental disorders. The aim of this study was to evaluate the effectiveness of sleep health education on sleep quality of cancer patients during chemotherapy stages.

Materials And Methods: In this clinical trial, 70 cancer patients were selected in the chemotherapy phase and divided into two groups of 35.

Potential drug-drug Interactions in hospitalized cancer patients: A report from the Middle-East.

Introduction: Patients suffering from solid tumors use a wide range of cytotoxic drugs. In this study, we aimed to detect, document, and descriptively analyze the potential drug-drug interactions in hospitalized solid tumor's patients in a Middle Eastern referral oncology-hematology University-affiliated hospital.

Materials And Methods: In this cross-sectional study, the medical record of solid tumor's patients who were admitted to the referral oncological center in Isfahan, Iran, during the six months period (2018) were considered.

Clinical Manifestations of β-Thalassemia Major in Two Different Altitudes; Bushehr and Shahrekord.

Background: Patients with β-thalassemia major (TM) develop iron overload through increased iron absorption and transfusional therapy and it's the most important complication of TM. Thalassemia is common in coastal regions and lands with low altitudes. The aim of this study is to determine the effect of high and low altitude on serum ferritin and treatment requirement in two groups of β-thalassemia major (TM) patients.

Effect of silymarin in the prevention of Cisplatin nephrotoxicity, a clinical trial study.

Background: Reno-protective effect of Silymarin was studied in some studies mainly on rats. In some of these studies, Silymarin was shown to have positive effects on preventing or decreasing severity of Cisplatin nephrotoxicity.

Objective: The aim of this study was to evaluate the protective effect of Silymarin on Cisplatin nephrotoxicity in adult patients with malignancy.

Association of Deficiency of Coagulation Factors (Prs, Prc, ATIII) and FVL Positivity with Preeclampsia and/or Eclampsia in Pregnant Women.

Background: Thrombophilia is a pathological state of increased blood coagulability. It causes problems during pregnancy including preeclampsia, stillbirth, repeated abortions, and detached pair. Out of the most prevalent factors causing inherited thrombophilia, protein S (Prs), protein C (Prc), and antithrombin III (ATIII) deficiency, and Factor V Leiden (FVL) mutation could be mentioned.

A randomized field trial for the primary prevention of osteoporosis among adolescent females: Comparison of two methods, mother centered and daughter centered.

Background: Osteoporosis is a serious public health. Since the majority of bone mass occurs during adolescence, primary prevention is important. Probably mother's participation in health education interventions leads to promote health behaviors in children.

Multiple myeloma presenting as acute tubulointerstitial nephritis and normal serum protein electrophoresis.

Multiple myeloma is uncommon in individuals younger than 40 years. Renal involvement is common in this disease, but acute tubulointerstitial nephritis is very rare. In 20% of patients, only the light chain is produced and serum protein electrophoresis is normal; however, in urine protein electrophoresis of these patients, the M spike is present.