Publications by authors named "Ali Firoozbakhtian"

Early detection of the coronavirus is acknowledged as a crucial measure to mitigate the spread of the pandemic, facilitating timely isolation of infected individuals, and disrupting the transmission chain. In this study, we leveraged the properties of synthesized Ag-MOF, including high porosity and increased flow intensity. Electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were employed to develop an economical and portable sensor with exceptional selectivity for COVID-19 detection.

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An innovative electrochemical sensor is introduced that utilizes bipolar electrochemistry on a paper substrate for detecting glucose in sweat. The sensor employs a three-dimensional porous nanocomposite (MXene/NiSm-LDH) formed by decorating nickel-samarium nanoparticles with double-layer MXene hydroxide. These specially designed electrodes exhibit exceptional electrocatalytic activity during glucose oxidation.

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Graphitic-phase carbon nitride (g-CN) materials have exhibited increasingly remarkable performance as emerging electrochemiluminescence (ECL) emitters, owing to their unique optical and electronic properties; however, the ECL merits of porous g-CN nanofibers doped with ternary metals are not yet explored. Deciphering the ECL properties of trimetal-doped g-CN nanofibers could provide an exquisite pathway for ultrasensitive sensing and imaging with impressive advantages of minimal background signal, great sensitivity, and durability. Herein, we rationally synthesized g-CN nanofibers doped atomically with Mn, Fe, and Co elements (Mn/Fe/Co/g-CN) in a one-pot via the protonation in ethanol and annealing process driven by the rolling up mechanism.

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Lactate is a metabolite that holds significant importance in human healthcare, biotechnology, and the food industry. The need for lactate monitoring has led to the development of various devices for measuring lactate concentration. Traditional laboratory methods, which involve extracting blood samples through invasive techniques such as needles, are costly, time-consuming, and require in-person sampling.

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Point-of-care testing plays a crucial role in diagnostics within resource-poor areas, necessitating the utilization of portable and user-friendly devices. The adaptation of biosensors for point-of-care applications requires careful considerations, such as miniaturization, cost-effectiveness, and streamlined sample processing. In recent years, the electrochemiluminescence (ECL) immunoassay has gained significant attention due to its visual detection capabilities and ability to facilitate high-throughput analysis.

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In recent years, the development of light-driven nanophotocatalysts has focused on efficiently eliminating organic pollutants. In this regard, the present work focuses on the photocatalytic removal of malachite green (MG) dye using cuttlebone powder (CB) modified with carbon quantum dots (CQDs)/nickel oxide (NiO) under visible light irradiation. Various techniques were used to characterize the proposed composite, including X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) images.

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Here, we report the fabrication of an enzyme-free glucose sensor benefiting from nickel-samarium nanoparticles-decorated MXene layered double hydroxide (MXene/Ni/Sm-LDH). The electrochemical response of the MXene/Ni/Sm-LDH to glucose was studied via cyclic voltammetry (CV). The fabricated electrode has high electrocatalytic activity for glucose oxidation.

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The unstoppable spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has severely threatened public health over the past 2 years. The current ubiquitously accepted method for its diagnosis provides sensitive detection of the virus; however, it is relatively time-consuming and costly, not to mention the need for highly skilled personnel. There is a clear need to develop novel computer-based diagnostic tools to provide rapid, cost-efficient, and time-saving detection in places where massive traditional testing is not practical.

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Researchers are constantly looking to find new techniques of virus detection that are sensitive, cost-effective, and accurate. Additionally, they can be used as a point-of-care (POC) tool due to the fact that the populace is growing at a quick tempo, and epidemics are materializing greater often than ever. Electrochemiluminescence-based (ECL) biosensors for the detection of viruses have become one of the most quickly developing sensors in this field.

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Coronavirus disease (COVID-19) is a new and highly contagious disease posing a threat to global public health and wreaking havoc around the world. It's caused by the Coronavirus that causes severe acute respiratory syndrome (SARS-CoV-2). In the current pandemic situation, rapid and accurate SARS-CoV-2 diagnosis on a large scale is critical for early-stage diagnosis.

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Article Synopsis
  • - C-reactive protein (CRP) is an important biomarker for detecting diseases like sepsis and cardiovascular conditions, as it indicates inflammation and can help in early diagnosis.
  • - A new CNT-based nanobiosensing system has been developed for quick, label-free detection of CRP, which can deliver results in as little as 8 minutes and has a low detection limit of 150 pM.
  • - The device demonstrates strong selectivity towards CRP over other proteins and maintains stability and reproducibility for at least 14 days, highlighting its potential for clinical use in monitoring CRP levels.
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Background: Medication adherence is a dynamic and complex behavioral process, which is strongly influenced by personal, social and environmental factors.

Objectives: To determine the prevalence and factors affecting non-adherence to medication among HIV-infected patients.

Design: A cross-sectional study.

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