No NLRP3 Inflammasome Expression in the Ouabain Animal Model of Bipolar Disorder.

Introduction Inflammation is believed to play a role in both bipolar illness and unipolar depression. Markers of inflammation are elevated during acute mood episodes. Specifically, gene expressions of the nucleotide-binding domain and leucine-rich repeat pyrin domain containing 3 ()-related proteins in peripheral blood have been purported to be upregulated in patients with bipolar disorder.

Identifying evidence informed psychological interventions during the COVID-19 pandemic: Rapid review of the literature.

•Less than a quarter of psychological interventions are developed based on evidence.•Evaluation of the effectiveness of existing online mental health resources is required.•Front-line healthcare providers experienced severe mental distress during COVID-19.

Early use of telepsychotherapy in resident continuity clinics-our experience and a review of literature.

Telepsychotherapy is an underutilized tool in training programs, and use of telepsychiatry often occurs in the later years of residency. This study evaluates the feasibility of early exposure to telepsychotherapy in residency continuity clinics and reviews the existing literature on the use of telemedicine in the training of psychiatrists. Feedback from the participating residents and patients was used to determine the benefit of such a training curriculum.

Use of the Electronic Health Record to Track Continuity of Care in Neurological Surgery Residency.

Background: Continuity of care in neurological surgery includes preoperative planning, technical and cognitive operative experience, and postoperative follow-up. Determining the extent of continuity of care with duty hour limits is problematic.

Objective: We used electronic health record data to track continuity of care in a neurological surgery program and to assess changes in rotation requirements.

Safety and efficacy of early thromboembolism chemoprophylaxis after intracranial hemorrhage from traumatic brain injury.

Object: Patients with traumatic brain injury (TBI) are at risk for development of thromboembolic disease. The use of chemoprophylaxis in this patient group has not fully been characterized. The authors hypothesize that early chemoprophylaxis in patients with TBI is safe and efficacious.

Can experienced physicians with high peripheral interventional volume but low carotid artery stenting (CAS) volume achieve low complication rates during CAS?

Aims: It has been stated that experienced physicians with a high volume of carotid artery stent (CAS) procedures have low complication rates, including cerebrovascular accidents (CVA). Complication rates, however, are not known for physicians with a low volume of CAS (<50 CAS/yr) but with a high volume of other peripheral endovascular procedures. Since the techniques used in CAS are similar to those used routinely in other peripheral interventions, we hypothesise that high volume peripheral interventional operators with appropriate training would have low complication rates during CAS procedures.

A novel catheter in patients with peripheral chronic total occlusions: a single center experience.

Objectives And Background: Recanalization of a chronic total occlusion (CTO) is technically challenging with less than optimum results in arterial disease. Crosser® is a novel technology that utilizes high frequency (20 KHz) vibration energy to fragment occlusive fibrous atherosclerotic plaque and helps in traversing the occluded vessel. We report a single center experience with this catheter as the primary device in peripheral chronic total occlusions.