Growth optimization, antibiogram, and molecular identification of Bacillus species isolated from the human gut.

The human microbial flora is quite diverse and versatile, playing several beneficial roles in association with the host and deriving nutrition from it. The present study aimed to identify gut microbial flora with potential probiotic activities. Eighteen bacterial isolates were screened from ten male individuals in this study.

Spontaneous spinal epidural hematoma following IV heparin and catheter-directed thrombolysis for deep vein thrombosis.

Spontaneous spinal epidural hematoma () is a rare condition, and it usually presents with acute onset neck or back pain, progressive weakness, and other symptoms of spinal cord compression. Catheter-directed thrombolysis is one option for limbs threatened by iliofemoral venous thrombosis; other options, such as venous thrombectomy (either open or percutaneous), are also available. There are few reported cases of SSEH owing to catheter-directed thrombolysis for deep venous thrombosis ().

The Rising Tide of Antibiotic Resistance: A Study on Extended-Spectrum Beta-Lactamase and Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae.

Background: The global spread of extended-spectrum beta-lactamase (ESBL)-producing and carbapenem-resistant Enterobacterales (CRE) poses a significant concern. Acquisition of antimicrobial resistance genes leads to resistance against several antibiotics, limiting treatment options. We aimed to study ESBL-producing and CRE transmission in clinical settings.

The effect of job and personal demands and resources on healthcare workers' wellbeing: A cross-sectional study.

The COVID-19 pandemic presented many psychological stressors which affected healthcare worker wellbeing. The aim of this study was to understand the factors that affect the wellbeing of healthcare professionals in the Kingdom of Saudi Arabia using Job-Demand and Resource (JD-R) Model. The proposal model consisted of demand factors (Work load-job demand, loneliness-personal demand), support factors (organizational support-job resource, and resilience-personal resource), mediators (burnout and work engagement), and outcome (wellbeing) A cross-sectional, descriptive study was conducted across 276 healthcare workers from hospitals and primary healthcare centers, including healthcare professionals, health associate professionals, personal care workers, health management and support personnel, and health service providers, and others between February-March 2022.

Impact of Clinical Presentation on Outcomes After Rotational Atherectomy in Patients Who Underwent Percutaneous Coronary Intervention.

Rotational atherectomy (RA) is widely used in the percutaneous treatment of heavily calcified coronary artery lesions in patients with chronic coronary syndromes (CCS). However, the safety and efficacy of RA in acute coronary syndrome (ACS) is not well established and is considered a relative contraindication. Therefore, we sought to evaluate the efficacy and safety of RA in patients presenting with non-ST-elevation myocardial infarction (NSTEMI), unstable angina (UA), and CCS.

Ticagrelor vs Prasugrel in a Contemporary Real-World Cohort Undergoing Percutaneous Coronary Intervention.

Background: Potent P2Y agents such as ticagrelor and prasugrel are increasingly utilized across the clinical spectrum of patients undergoing percutaneous coronary intervention (PCI). There is a paucity of data supporting their use in a patient population inclusive of both acute coronary syndrome (ACS) and chronic coronary syndrome (CCS) patients.

Objectives: The authors compared the efficacy and safety of ticagrelor and prasugrel in a real-world contemporary PCI cohort.

Molecular Characterization of Bacterial Isolates from Soil Samples and Evaluation of their Antibacterial Potential against MDRS.

Some soil microbes, with their diverse inhabitance, biologically active metabolites, and endospore formation, gave them characteristic predominance and recognition among other microbial communities. The present study collected ten soil samples from green land, agricultural and marshy soil sites of Khyber Pakhtunkhwa, Pakistan. After culturing on described media, the bacterial isolates were identified through phenotypic, biochemical and phylogenetic analysis.

The evaluation of antibiotic susceptibility pattern and associated risk factors of UTI in tertiary care hospital of Peshawar.

UTIs are majorly caused by species of bacteria in patients of almost all ages. The study was aimed to determine the prevalence rate of uropathogens, its antibiotic susceptibility pattern and associated risk factors. Urine samples were collected from n=470 participants using sterilized containers and were inoculated on culture media.

Improving the performance of mini-channel heat sink by using wavy channel and different types of nanofluids.

The combination of nano fluid and changing cross-section mini-channel heat sink effects have become a remarkable choice for the use of thermal devices such as miniature electronic devices to be effectively cooled. In this paper, the comparison of three dimensional straight and wavy channel configuration with using different types nano fluids are numerically investigated. The effects of wave amplitude and A particular type of volume fraction of (Copper Oxide CuO, Dimond AlO, Iron Oxide FeO, Titanium Oxide TiO and Silver Ag-nano fluids are offered.

Comparative in vitro activity of selected antibacterial agents against Escherichia coli isolated from hospitalized patients suffering UTI.

Escherichia coli is the most studied among those bacteria causing urinary tract infections. This study was aimed to find out antibacterial activity and minimum inhibitory concentration of selected antibacterial agents against E. coli isolates of hospitalized UTI patients.

MHD mixed convection and entropy generation of CNT-water nanofluid in a wavy lid-driven porous enclosure at different boundary conditions.

In this study, Galerkin Finite Element Method or GFEM is used for the modeling of mixed convection with the entropy generation in wavy lid-driven porous enclosure filled by the CNT-water nanofluid under the magnetic field. Two different cases of boundary conditions for hot and cold walls are considered to study the fluid flow (streamlines) and heat transfer (local and average Nusselt numbers) as well as the entropy generation parameters. Richardson (Ri), Darcy (Da), Hartmann angle (γ), Amplitude (A), Number of peaks (N), Volume fraction (φ), Heat generation factor (λ), Hartmann number (Ha) and Reynolds number (Re) are studied parameters in this study which results indicated that at low Richardson numbers (< 1) increasing the inclined angle of magnetic field, decreases the Nu numbers, but at larger Richardson numbers (> 1) it improves the Nu numbers.

Predicting Health Care Providers' Acceptance of a Personal Health Record Secure Messaging Feature.

Background: Personal health records (PHRs) can facilitate patient-centered communication through the secure messaging feature. As health care organizations in the Kingdom of Saudi Arabia implement PHRs and begin to implement the secure messaging feature, studies are needed to evaluate health care providers' acceptance.

Objective: The aim of this study was to identify predictors of health care providers' behavioral intention to support the addition of a secure messaging feature in PHRs using an adapted model of the Unified Theory of Acceptance and Use of Technology as the theoretical framework.

Health Care Providers' Acceptance of a Personal Health Record: Cross-sectional Study.

Background: Personal health records (PHRs) are eHealth tools designed to support patient engagement, patient empowerment, and patient- and person-centered care. Endorsement of a PHR by health care providers (HCPs) facilitates patient acceptance. As health care organizations in the Kingdom of Saudi Arabia begin to adopt PHRs, understanding the perspectives of HCPs is important because it can influence patient adoption.

Comparative Effect of Fertilization Practices on Soil Microbial Diversity and Activity: An Overview.

Continuously increasing human population demands increased food production, which needs greater fertilizer's input in agricultural lands to enhance crop yield. In this respect, different fertilization practices gained acceptance among farmers. We reviewed effect of three main fertilization practices (Conventional-, Organic-, and Bio-fertilization) on soil microbial diversity, activity, and community composition.

Detection of Diabetic Eye Disease from Retinal Images Using a Deep Learning Based CenterNet Model.

Diabetic retinopathy (DR) is an eye disease that alters the blood vessels of a person suffering from diabetes. Diabetic macular edema (DME) occurs when DR affects the macula, which causes fluid accumulation in the macula. Efficient screening systems require experts to manually analyze images to recognize diseases.

Predicting Patients' Intention to Use a Personal Health Record Using an Adapted Unified Theory of Acceptance and Use of Technology Model: Secondary Data Analysis.

Background: With the rise in the use of information and communication technologies in health care, patients have been encouraged to use eHealth tools such as personal health records (PHRs) for better health and well-being services. PHRs support patient-centered care and patient engagement. To support the achievement of the Kingdom of Saudi Arabia's Vision 2030 ambitions, the National Transformation program provides a framework to use PHRs in meeting the 3-fold aim for health care-increased access, reduced cost, and improved quality of care-and to provide patient- and person-centered care.

Understanding the impact of information sources on COVID-19 related preventive measures in Finland.

The COVID-19 pandemic amplified the influence of information reporting on human behavior, as people were forced to quickly adapt to a new health threatening situation by relying on new information. Drawing from protection-motivation and cognitive load theories, we formulated a structural model eliciting the impact of the three online information sources: (1) social media, (2) official websites, and (3) other online news sources; on motivation to adopt recommended COVID-19 preventive measures. The model was tested with the data collected from university employees and students (n = 225) in March 2020 through an online survey and analyzed using partial least square structural equation modeling (PLS-SEM).

Magnetic nanofluid behavior including an immersed rotating conductive cylinder: finite element analysis.

In this paper, numerical Galerkin Finite Element Method (GFEM) is applied for conjugate heat-transfer of a rotating cylinder immersed in FeO-water nanofluid under the heat-flux and magnetic field. The outer boundaries of the cavity were maintained at low temperatures while beside the cylinder were insulated. It is assumed that the cylinder rotates in both clockwise and counter-clockwise directions.

Antibiogram of ESBL and MBL producing Pseudomonas aeruginosa among the population of Hazara division, KPK, Pakistan.

Objective: To investigate the frequency rate and sensitivity pattern of extended-spectrum beta-lactamase and metallobeta- lactamase producing Pseudomonas aeruginosa isolated from major hospitals.

Methods: The cross-sectional study was conducted in the Microbiology section of the Pathology Department of Ayub Medical College, Abbottabad, Pakistan, from September 2017 to April 2018, and comprised clinical samples collected from different medical wards of major hospitals in the study area. For the selective growth of Pseudomonas aeruginosa, Cetrimide agar was used, and different antibiotics were evaluated for the sensitivity pattern following Kirby-Bauer diffusion method.

From information seeking to information avoidance: Understanding the health information behavior during a global health crisis.

Individuals seek information for informed decision-making, and they consult a variety of information sources nowadays. However, studies show that information from multiple sources can lead to information overload, which then creates negative psychological and behavioral responses. Drawing on the Stimulus-Organism-Response (S-O-R) framework, we propose a model to understand the effect of information seeking, information sources, and information overload (Stimuli) on information anxiety (psychological organism), and consequent behavioral response, information avoidance during the global health crisis (COVID-19).

MHD effect on mixed convection of annulus circular enclosure filled with Non-Newtonian nanofluid.

The fluid flow and mixed convection heat transfer of a non-Newtonian (Cu-water) nanofluid-filled circular annulus enclosure in a magnetic field are investigated numerically for a two-dimensional, steady-state, incompressible, laminar flow using the Galerkin finite element method (GFEM). The Prandtl number (Pr = 6.2) and Grashof number (Gr = 100) are assumed to be constants, whereas the Richardson number varies within a range of 0 ≤ Ri ≤ 1, the Hartman number within a range of 0 ≤ Ha ≤60, the Power law index within a range of 0.

Impact of Online Information on Self-Isolation Intention During the COVID-19 Pandemic: Cross-Sectional Study.

Background: During the coronavirus disease (COVID-19) pandemic, governments issued movement restrictions and placed areas into quarantine to combat the spread of the disease. In addition, individuals were encouraged to adopt personal health measures such as social isolation. Information regarding the disease and recommended avoidance measures were distributed through a variety of channels including social media, news websites, and emails.

Late Onset Invasive Pulmonary Aspergillosis in Lung Transplant Recipients in the Setting of a Targeted Prophylaxis/Preemptive Antifungal Therapy Strategy.

Background: Invasive pulmonary aspergillosis (IPA) is a significant cause of morbidity and mortality in lung transplant recipients (LTRs). It is unclear how a targeted prophylaxis/ preemptive antifungal therapy strategy impacts the incidence of IPA beyond the first-year posttransplant.

Methods: This is a retrospective cohort of LTRs from January 2010 to December 2014.