Introduction: The aim of the present study was to compare the amount of apical debris extrusion after preparation using hand files, reciprocating files, and full rotary nickel-titanium systems.
Methods And Materials: One hundred extracted human mandibular molars with two separated canals in mesial root were divided into five groups and prepared using reciprocating systems (Reciproc file and Safesider endodontic reamers file), full rotary systems (Mtwo and Neoniti A1 files) and hand instrumentation systems. Endodontic access was prepared and a #15 K-file was passed beyond the apex of the mesiobuccal canal by 1 mm to ensure the canal patency.