Outcomes and success of amniotic membrane transplantation for the treatment of corneal diseases.

Purpose: The amniotic membrane (AM), the inner layer of the placenta, is a semitransparent, avascular, and thin tissue that is useful due to its structure. Amniotic membrane transplantation (AMT) avoids the need for keratoplasty to prevent corneal perforating. The purpose of the study was to evaluate the visual (gain of or no change in visual acuity) and corneal outcomes (closure of the ulcer or corneal healing) of AMT in patients with ocular surface diseases.

Short-term effect of macular edema on the peripapillary retinal nerve fiber layer in patients with wet age-related macular degeneration and diabetic macular edema: A comparative study.

Background: The combined presence of glaucoma and age-related macular degeneration (ARMD), or glaucoma and diabetes mellitus (DM), occur fairly frequently, especially in elderly patients. This study was intended to compare the effect of resolving macular edema due to DM and wet ARMD on peripapillary retinal nerve fiber layer (RNFL) thickness.

Methods: This cross-sectional study included 76 patients with macular edema secondary to DM (n = 40, 52.

The Effect of Mask Use on the Ocular Surface During the COVID-19 Pandemic.

Objectives: The new coronavirus disease 2019 (COVID-19) pandemic emerged in Wuhan, China in October 2019 and spread rapidly all over the world, making extended mask use an inescapable rule of daily life. Literature data indicate that the use of face masks increases the symptoms of dry eye in addition to preventing the spread of COVID-19. The aim of our study was to evaluate the relationship between the clinical signs and symptoms of dry eye and the duration of mask use in healthy individuals using regular face masks.

Optic nerve head microvascular characteristics in patients with unilateral pseudoexfoliation syndrome: an optical coherence tomography angiography study.

Purpose: To compare vascular microcirculation changes of the optic nerve head (ONH) and to evaluate the peripapillary retinal nerve fiber layer (RNFL) in the patients with unilateral pseudoexfoliation syndrome (PEXS), other eyes of these patients without PEXS and healthy control eyes using optical coherence tomography angiography (OCTA) and spectral domain optical coherence tomography (SD-OCT).

Methods:  This cross-sectional study enrolled 29 pseudoexfoliative (PEX) and 29 fellow eyes of patients with unilateral PEXS, and 28 healthy eyes as controls. According to inclusion criteria the study group with asymmetric PEXS were normotensive and no glaucoma diagnosis.

Correlation of Ocular Biometric Parameters and Macular Ganglion Cell Layer in Normal Eyes.

Purpose: To determine the association between ocular biometric parameters and macular ganglion cell layer (MGCL) thickness in normal eyes.

Methods: This observational cohort study was conducted with 76 eyes of 76 healthy subjects. Keratometry, pachymetry, corneal volume, iridocorneal angle were measured with Sirius (CSO, Florence, Italy); axial length, anterior chamber depth, anterior chamber volume, corneal diameter were measured with IOL Master (Carl Zeiss Meditec, Dublin, California).

Is macular pigment optical density really involved in fixation preference?

Purpose: To evaluate macular pigment optical density in healthy children and to compare the values with those of strabismic children with respect to fixation preference.

Methods: The study recruited 54 healthy and 41 strabismic children. Two groups were matched in terms of gestational age, birth weight, and body mass index.

Assessment of corneal backward light scattering in the healthy cornea and factors affecting corneal transparency.

Purpose: To quantify normative corneal optical density (COD) values of healthy individuals and to investigate alterations in the COD in relation to their ocular and demographic characteristics.

Study Design: Prospective, cross-sectional, and observational.

Methods: In total, 588 eyes from 588 healthy participants with clear corneas were consecutively enrolled.

Relationship between anterior segment and optic nerve head parameters in healthy subjects.

Purpose: To determine the relationship between anterior segment and optic nerve head (ONH) parameters.

Methods: Two hundred healthy subjects were enrolled in this study. The par-ticipants underwent measurement of anterior segment parameters with a Pentacam Scheimpflug system and imaging of the optic disc with confocal scanning laser ophthalmoscopy.

Intravitreal Bevacizumab and Ranibizumab in the Treatment of Acute Central Serous Chorioretihopathy: A Single Center Retrospective Study.

Objectives: To evaluate and compare the anatomical and functional outcomes of patients with acute central serous chorioretinopathy (CSC) who did not receive any intervention or treatment with intravitreal bevacizumab or ranibizumab.

Methods: A single-center retrospective comparative study. Seventy eyes of 70 patients were recruited for the study; 27 patients were only observed without any medication or intervention (observation group), 23 were treated with intravitreal bevacizumab (IVB group), and the remaining 20 were treated with intavitreal ranibizumab (IVR group).

Evaluation of biomechanical properties of the cornea in patients with primary hyperparathyroidism.

The purpose of this study is to compare the corneal biomechanical properties in primary hyperparathyroid patients and healthy control subjects. The study consisted of 31 patients with primary hyperparathyroidism (study group) and 31 healthy subjects (control group). Corneal biomechanical properties, including corneal hysteresis (CH), corneal resistance factor (CRF), and intraocular pressure (IOP) were measured with an ocular response analyzer (ORA).

Effect of Pseudoexfoliation on Corneal Transparency.

Purpose: To perform a comparison of the corneal optical density (COD) parameters in eyes with pseudoexfoliation syndrome (PES) and age-matched controls.

Methods: This study was designed as a prospective cross-sectional study. Pentacam HR-Scheimpflug imaging system was used to observe the COD of PES, normal fellow, and normal control eyes.

Oxidant/antioxidant balance in the aqueous humor of patients with glaucoma.

Aim: To evaluate total antioxidant status (TAS), total oxidant status (TOS), and the oxidative stress index (OSI) of the aqueous humor (AH) in patients with glaucoma.

Methods: The prospective study was composed of a study group (n=31) and a control group (n=31). Fifteen patients in the study group were diagnosed with primary open angle glaucoma (POAG), and 16 patients were diagnosed with pseudoexfoliation glaucoma (PEG).

Disturbed oxidant/antioxidant balance in aqueous humour of patients with exfoliation syndrome.

Purpose: To establish the total oxidant status (TOS), total antioxidant capacity (TAC) and oxidative stress index (OSI) of the aqueous humour in patients presenting exfoliation syndrome (EXS) without glaucoma.

Methods: The TOS, TAC and OSI of the aqueous humour of patients with EXS (group 1, n = 17) and patients without EXS (group 2, n = 25) who underwent cataract surgery were evaluated. Samples were measured spectrophotometrically using a colourimetric method.

Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopathy.

Aim: To measure changes of total oxidant status (TOS) and total antioxidant capacity (TAC) of aqueous humor (AH) in diabetic retinopathy (DR) patients, and to determine if there were any differences in TOS and TAC of AH in diabetic patients without retinopathy compared with non-diabetic patients.

Methods: One hundred and three eyes of 103 patients who were enrolled for cataract surgery were included in this study. Patients were grouped according to presence of diabetes and stage of DR.

Optic disc and retinal nerve fiber layer parameters of eyes with keratoconus.

Background And Objective: To evaluate optic nerve head (ONH) characteristics and retinal nerve fiber layer (RNFL) thickness measurements in patients with nonglaucomatous keratoconus.

Patients And Methods: This was a cross-sectional, observational study in which 46 patients with keratoconus and 74 healthy subjects were included. Analysis of ONH and RNFL imaging were performed by confocal scanning laser ophthalmoscopy and optical coherence tomography, respectively.

Topographic differences between large and normal optic discs: a confocal scanning laser ophthalmoscopy study.

Purpose: The aim of the study was to investigate the optic nerve head parameters of healthy macrodiscs to provide standard measurements for them to be the basis for future quantitative comparisons.

Methods: Sixty-nine subjects with macrodisc (disc area larger than 2.82 mm(2)) and 91 healthy controls (disc area between 1.

Comparison of the outcome of repeat trabeculectomy with adjunctive mitomycin C and initial trabeculectomy.

Purpose: To compare the efficacy and safety of repeat and initial trabeculectomy with mitomycine C (MMC).

Methods: Eighty seven patients, who had underwent repeat (repeat group) or initial (initial group) trabeculectomy with MMC, were enrolled in this prospective trial. Postoperative outcome measures included the amount of decrease in intraocular pressure (IOP), the number of anti-glaucoma medications, and the complications.

Ocular response analyzer to assess corneal biomechanical properties in exfoliation syndrome and exfoliative glaucoma.

Background: The aim of this work was to investigate the differences in corneal biomechanical parameters between healthy and exfoliation syndrome (EXS) and exfoliative glaucoma (EXG) patients.

Methods: Two hundred and forty-four eyes of 102 healthy, 64 EXS, and 78 EXG patients were included in the study. Corneal biomechanical parameters were measured using an ocular response analyzer (ORA).

Impact of panretinal photocoagulation on optic nerve head parameters.

Background: To investigate the impact of panretinal photocoagulation (PRP) on quantitative optic nerve head (ONH) assessment in patients with diabetic retinopathy.

Methods: Eighty eyes of 80 diabetic patients who did not undergo PRP and 45 eyes of 45 subjects with diabetes who underwent PRP were enrolled in the prospective, cross-sectional study. Participants were evaluated by confocal scanning laser ophthalmoscopy (CSLO).

Scanning laser ophthalmoscopic parameters of eyes with exfoliation syndrome.

Purpose: To evaluate optic nerve head (ONH) characteristics in patients with exfoliation syndrome (EXS).

Methods: This was a cross-sectional, observational study in which 73 eyes from 73 patients with EXS and 93 eyes from 93 age-matched healthy subjects who met the inclusion criteria were included. Topographic measurements of the ONH and peripapillary retinal nerve fiber layer (RNFL) thickness were performed by confocal scanning laser ophthalmoscopy, using a Heidelberg retina tomograph.

Alterations in anterior chamber depth in primary open-angle glaucoma patients during latanoprost therapy.

Purpose: The aim of this study was to evaluate changes in the anterior chamber depth (ACD) in primary open-angle glaucoma (POAG) patients during latanoprost therapy.

Methods: We carried out a prospective study in which we enrolled 66 newly diagnosed POAG patients treated with latanoprost 0.005% (group 1) and 50 ocular hypertensive and ⁄ or glaucoma suspect cases who were given no therapy (group 2 [control]).