Publications by authors named "Ali Budak"

Article Synopsis
  • The study assessed the impact of Rhinapi nasal spray on allergic rhinitis symptoms among 10,000 participants in Turkey over a 3-week period.
  • The treatment led to significant improvements in total symptom scores, quality of life (QoL) scores, and otolaryngological examination scores, with statistically significant changes before and after usage.
  • The findings suggest that Rhinapi effectively reduces symptoms of allergic rhinitis and can be considered as an additional treatment option for those affected.
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Article Synopsis
  • Major lower limb amputations pose a significant risk of mortality, with 30-day, one-year, and three-year mortality rates reported at 16.6%, 38.3%, and 60.1%, respectively.
  • The study involved 193 patients, mostly aged 65 and older, with conditions like diabetes and peripheral artery disease leading to the amputations.
  • Key risk factors impacting mortality included older age (≥65 years), diabetes, and renal failure, highlighting the need for improved patient management and care post-amputation.
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Objective: To compare the results of endovascular therapy for chronic limb-threatening ischemia (CLTI) in patients categorized under the gray and yellow zones of the patient risk, limb severity, and anatomic pattern (PLAN) concept over a 2-year follow-up period.

Methods: Patients who underwent endovascular therapy for peripheral artery disease and presented with CLTI from February 2017 to February 2019 were retrospectively reviewed. The patients were grouped into yellow and gray zones based on the PLAN concept.

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The authors performed a detailed retrospective analysis of diabetic patients undergoing isolated coronary artery bypass graft surgery aiming to investigate the association of the preoperative glycosylated hemoglobin with occurrence of postoperative atrial fibrillation. Although statistical analysis showed a weak relationship between HbA1c values of 9.06% or above and postoperative atrial fibrillation (PoAF), they concluded that serum level of HbA1c could not be used as a predictor for the development of PoAF.

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The authors conducted a prospective, observational study to evaluate the correlation of fluid responsiveness with commonly used carotid Doppler-derived indices like carotid artery blood flow, carotid corrected flow time, respirophasic variation in carotid artery blood flow peak velocity in patients undergoing coronary artery bypass grafting. They claimed that altough only ΔVpeak demonstrated some predictive power with areas under receiver operating characteristic of 0.671, carotid Doppler ultrasound indices were found to be not dependable as a substitute for invasive methods to assess fluid responsiveness.

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Background: We have analyzed our single-center immediate and follow-up results in the management of acute iliofemoral deep vein thrombosis (IFDVT) using pharmacomechanical catheter-directed thrombolysis (PMCDT) to determine the safety, accuracy, and effects on quality of life and whether this treatment strategy prevents post-thrombotic syndrome (PTS).

Methods: The cases of 230 patients who had undergone PMCDT to treat IFDVT from January 2017 to December 2018 were retrospectively reviewed. The preoperative, operative, and postoperative variables, Marder scores, outcomes, and follow-up assessments with the Villalta score and venous clinical severity score were investigated.

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The authors present a revolutionary study aiming to evaluate the effect of alterations in potassium concentrations in transfused packed red blood cells (PRBC) on the neonate and infant potassium levels after congenital cardiac surgery. By establishing a strict protocol that restricts the rate of transfusion, the age of the transfused PRBC, and not transfusing a PRBC with a potassium level above 15 mmol/L, they accomplished to suggest a safe and easy way for preventing transfusion-associated hyperkalemia.

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Objectives: The aim of this study is to evaluate the safety and efficacy of the novel bidirectional cannula that ensures stable distal perfusion compared to conventional cannula in patients undergoing femoral arterial cannulation for cardiopulmonary bypass (CPB).

Methods: During a 1-year period, 64 patients undergoing surgery via peripheral cannulation were prospectively randomized to receive 19 F bidirectional (Biflow™, LivaNova, Italy) or 19 F conventional (HLS Peripheral cannula, Getinge Group™, Germany) cannula with 6 F downstream line (Bicakcilar™, Turkey) for femoral artery cannulation. The primary outcome included the efficacy (adequacy of antegrade/retrograde comparative flow via cannula measured by doppler ultrasonography) and the secondary outcome was the safety (early/late complications and adverse events).

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We present our multidisciplinary and multistep strategy in patients undergoing minimally invasive aortic valve replacement (mAVR) on minimally invasive extracorporeal circulation (MiECC) compared with control groups of a single strategy and conventional techniques. This cohort study included high-risk patients (Society of Thoracic Surgeons [STS] risk score >8%) undergoing aortic valve surgery under different strategies during the period from January 2017 until March 2019. Patients were matched for age, gender, body mass index, and STS score: group 1 (MiAVR) based on a minimally invasive technique with J-mini-sternotomy, rapid deployment valve (RDV), and type IV customized MiECC; group 2 (control-mAVR) consisted of minimally invasive technique with only J mini-sternotomy and RDV on a conventional extracorporeal system; group 3 (control-MiECC): full sternotomy and type IV customized MiECC; and group 4 (control): full sternotomy on a conventional extracorporeal system.

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Aim: Postoperative bleeding is a significant cause of morbidity and mortality in patients undergoing cardiac surgery. Studies have been conducted, and guidelines have been published regarding patient blood management and aiming to prevent blood loss in the perioperative period. Various bleeding risk assessments were developed for preoperative period.

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Objective: Several types of nasal packs are used postoperatively in septoplasty. In this study, we compared two commonly used nasal packing materials, the intranasal septal splint with airway and Merocel tampon, in terms of pain, bleeding, nasal obstruction, eating difficulties, discomfort in sleep, and pain and bleeding during removal of packing in the early period.

Methods: The study group included 60 patients undergoing septoplasty.

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Background: Despite the recent introduction of a number of technical and pharmacologic blood conservation measures, bleeding and allogeneic transfusion remain persistent problems in open-heart surgical procedures. Efforts should be made to decrease or completely avoid transfusions to avoid these negative reactions.

Methods: Our coronary artery bypass grafting database was reviewed retrospectively and a total of 243 patients who underwent cardiac surgery with cardiopulmonary bypass (CPB) were studied in a 12-month period (January-December 2016) after the implementation of the new program, and compared with 275 patients of the previous 12-month period.

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Background: The primary objective of this study was to test and compare the efficacy of currently available intraoperative blood salvage systems via a demonstration of the level of increase in percentage concentration of red blood cells (RBC), white blood cells 9WBC) and platelets (Plt) in the end product.

Methods: In a prospective, randomized study, data of 80 patients undergoing elective cardiac surgery with cardiopulmonary bypass in a 6-month period was collected, of which the volume aspirated from the surgical field was processed by either the HemoSep Novel Collection Bag (Advancis Surgical, Kirkby-in-Ashfield, Notts, UK) (N=40) (Group 1) or a cell- saver (C.A.

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Objective: One thousand consecutive patients who underwent endovascular repair in an 8-year period were studied retrospectively to evaluate technical success, freedom from reinterventions, early clinical outcome, and risk factors for restenosis/occlusion.

Methods: Mean ± SD Rutherford class was 3.29 ± 0.

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Objective: The objective of this study was to evaluate the causes of persistent nasal obstruction of patients after septoplasty.

Materials And Methods: After exclusion of allergic rhinitis, non-allergic rhinitis and nasal polyposis, this study included 90 patients with nasal breathing problem who underwent septoplasty at least 4 months ago. After taking full history and completing otorhinological and endoscopic examination, all patients graded their extent of obstruction using the Nasal Obstruction Symptoms Evaluation scale.

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Aim: Paraplegia due to ischemia-reperfusion (I/R) injury of the spinal cord is a devastating complication of thoracoabdominal aortic surgery. Cysteinyl leukotrienes are potent mediators of inflammation that are associated with I/R injury. The present study was designed to investigate the role of montelukast, a selective reversible CysLT1 receptor antagonist, on spinal cord I/R injury in an experimental model.

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Left ventricular pseudo-aneurysms develop when cardiac rupture is contained by pericardial adhesions or scar tissue due to myocardial infarction, surgery, trauma or infection. Left ventricular pseudo-aneurysms are uncommon, difficult to diagnose and prone to cardiac rupture. Urgent surgical repair is recommended.

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Objectives: To evaluate the effect of weight percentile on deep neck infections in children.

Methods: A retrospective evaluation of 79 patients who were treated for deep neck infections. The patients were divided into six groups according to weight percentile.

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Objective: Early and medium-term improvement of functional capacity and regression of left ventricular hypertrophy was evaluated in the young adult patient group following application of 21 mm or 23 mm bileaflet aortic mechanical valve prosthesis due to aortic stenosis. Methods : Twenty two patients (10 male, 12 female; mean age 27+-8.2 (19-43)) who underwent isolated aortic valve replacement due to rheumatic aortic stenosis, were included in the study.

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Introduction: Modern surgical management of chronic venous insufficiency is possible since the development of catheter-based minimally invasive techniques, including radiofrequency ablation (RFA) and the application of colour Doppler sonography. RFA technology requires the use of tumescent anaesthesia, which prolongs the operating time. Instilling tumescent anaesthesia percutaneously below the saphenous fascia is the steepest part of the learning curve.

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Since the first successful application of the heart-lung machine in 1953 by John Gibbon [1], great efforts have been made to modify the bypass techniques and devices in order to allow prolonged extracorporeal circulation in the intensive care unit (ICU), commonly referred to as extracorporeal membrane oxygenation (ECMO). ECMO uses classic cardiopulmonary bypass technology to support circulation. It provides continuous, non-pulsatile cardiac output and extracorporeal oxygenation [2].

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