Publications by authors named "Ali Buckland"

Article Synopsis
  • Mitochondrial donation is now legally allowed in Australia to help prevent the passing of mitochondrial diseases from mothers to their children as part of a clinical trial.
  • A systematic literature review analyzed five cohort studies and 19 case reports on how mitochondrial disease affects pregnancy.
  • While many women with mitochondrial disease experience no negative health effects during pregnancy, there is a risk of serious complications, leading to proposed guidelines for preconception counseling and antenatal care.
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Background: Myelin oligodendrocyte glycoprotein (MOG) IgG seropositivity is a prerequisite for MOG antibody-associated disease (MOGAD) diagnosis. While a significant proportion of patients experience a relapsing disease, there is currently no biomarker predictive of disease course. We aim to determine whether MOG-IgG epitopes can predict a relapsing course in MOGAD patients.

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Primary leptomeningeal melanomas are rare, comprising less than one percent of all brain tumours. They are aggressive and radioresistant tumours, with a poor prognosis. The mainstay of treatment is complete surgical resection and chemotherapy with limited success.

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Background And Objectives: Voice abnormality is a frequent finding in school age children born at <25 weeks' gestation in Western Australia. The objective of this study was to determine the frequency of voice abnormality, voice-related quality of life, and demographic and intubation factors in this population.

Methods: Survivors <25 weeks' gestational age in Western Australia born from 1996 to 2004 were included.

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Objectives/hypothesis: Instrumental measures of voice allow practitioners to assess the severity of voice disorders and objectively measure treatment outcomes. Instrumental measures should be calculated on both sustained vowel and connected speech samples to ensure ecological validity. However, there is a lack of appropriate, validated acoustic measurements for use in the pediatric population.

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