Publications by authors named "Ali Barreh Guedi"
J Neural Transm (Vienna)
August 2024
Article Synopsis
- Glutathione S-transferases (GSTs) play a role in oxidative stress linked to Parkinson's disease (PD), with a study focused on how GSTM1 and GSTT1 genetic variations affect PD characteristics in Tunisian patients.
- The research involved 300 PD patients and found that individuals with inactive GSTM1/GSTT1 had a 2.5 times greater risk of developing PD and experienced specific symptoms like tremors and asymmetric onset.
- Patients with active GST genes showed better treatment responses and lower motor impairment, while those with inactive genes faced memory issues and attention deficits, indicating a need for further research on the long-term effects of GST polymorphisms in PD progression.
