In this paper, a novel phononic crystal fiber with conical input is introduced for coupling environmental acoustic waves to the fiber core. Environmental acoustic waves can be focused and coupled to the core through conical input. In the first step, a cone shape coupler has been considered for coupling the incident acoustic waves to the core region.
View Article and Find Full Text PDFNeuronal death, decreased activity or dysfunction of neurotransmitters are some of the pathophysiological reasons for neurodegenerative diseases like Alzheimer's, Parkinson's and multiple sclerosis. Also, there is evidence for the role of infections and infectious agents in neurodegenerative diseases and the effect of some metabolites in microorganisms in the pathophysiology of these diseases. In this study, we intend to evaluate the existing studies on the role of infectious agents and their metabolites on the pathophysiology of neurodegenerative diseases.
View Article and Find Full Text PDFThe commercial production of multifunctional, biocompatible, and biodegradable biopolymers such as poly-γ-glutamic acid via microbial fermentation requires the development of simple and cheap methods for mass production. This study optimized the poly-γ-glutamic acid production of Bacillus licheniformis ATCC 9945 in several steps. At first, the most critical components of the culture medium, including l-glutamic acid, citric acid, and glycerol, were selected by screening nine factors through the Plackett-Burman experimental design and then were optimized using the response surface method and the central composite design algorithm.
View Article and Find Full Text PDFA concentric cylindrical cloak is showed here to achieve the acoustic cloaking phenomenon. The introduced structure consists of MNE layers and water in MNE substrate in the MHz frequency range. Due to avoiding the incoming acoustic waves by the shell, the object can be hidden inside the cylindrical area of any shape.
View Article and Find Full Text PDFIn this investigation, a phononic crystal-based fiber is proposed for energy harvesting application in metalworking factories. Phononic crystal plays the role of cladding in elastic fiber structure. Each of single-core fibers includes a tungsten hollow cylinder in central region which its internal radius is different in three single-core fibers.
View Article and Find Full Text PDFSARS-CoV-2 is a novel coronavirus and the cause of the recent pandemic; it is an enveloped -coronavirus. SARS-CoV-2 appear in the Wuhan City of China for the first time and outspread worldwide quickly. Due to its person-to-person fast transmission, COVID-19 is becoming a global problem.
View Article and Find Full Text PDFPoly-γ-glutamic acid (-PGA) is a versatile biopolymer with widespread applications in the food, pharmaceutical, and medical industries. One of the main challenges in expanding -PGA industrial applications is the high cost of production. Developing an efficient and low-cost fermentation process such as bacterial cultivation with pulsed feeding can significantly reduce production costs.
View Article and Find Full Text PDFIn this study, a novel elastic phononic crystal fiber has been presented for the first time. This proposed structure can expand the sonic communications field, significantly. In order to realize the elastic fiber performance, solid-solid phononic crystal has been utilized.
View Article and Find Full Text PDFMany aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been studied to determine its properties, transmission mechanisms, and pathology. These efforts are aimed at identifying potential approaches to control or treat the disease. Early treatment of novel SARS-CoV-2 infection to minimize symptom progression has minimal evidence; however, many researchers and firms are working on vaccines, and only a few vaccines exist.
View Article and Find Full Text PDFAll the world is involved in the COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is a positive-sense RNA and has an envelope. There is no specific drug for this disease and treatment methods are limited.
View Article and Find Full Text PDFCyclophosphamide (CTX) has been broadly used in the clinic for the treatment of autoimmune disorders and ovarian cancer. The process of chemotherapy has significant toxicity in the reproductive system as it has detrimental effects on folliculogenesis, which leads to an irreversible premature ovarian failure (POF). Coenzyme Q10 (CoQ10) has positive impacts on the reproductive system due to its antioxidant properties, protecting the cells from free-radical oxidative damage and apoptosis.
View Article and Find Full Text PDFTumour Biol
November 2016
Background: Bacterial Extracellular Polymeric Substances (EPS) are environmental friendly and versatile polymeric materials that are used in a wide range of industries such as: food, textile, cosmetics, and pharmaceuticals. To make the production process of the EPS cost-effective, improvements in the production yield is required which could be implemented through application of processes such as optimized culture conditions, and development of the strains with higher yield (. through genetic manipulation), or using low-cost substrates.
View Article and Find Full Text PDFJ Environ Health Sci Eng
August 2015
Regarding fast development of the nanotechnology and the probably of it's side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O.
View Article and Find Full Text PDFTumour Biol
June 2015
Cisplatin (CP) is a remarkably effective Pt-based anticancer drug, but it also exhibits severe toxic side effects, including nephrotoxicity and ototoxicity, and CP nephrotoxicity is a major constraint for the treatment of solid tumors. This study was designed to evaluate the electrolyte and biochemical changes in dogs with acute kidney injury (acute renal failure) following administration of CP as a chemotherapeutic agent to exhibit broad efficacy in solid tumors. A total of 10 adult male dogs were selected (treated dogs = 7 and control dogs = 3).
View Article and Find Full Text PDFRigorous methods for design and verification of health IT systems have lagged far behind their proliferation. The inherent technical complexity of healthcare, combined with the added complexity of health information technology makes their resulting behavior unpredictable and introduces serious risk. We propose to mitigate this risk by formalizing the relationship between HIT and the conceptual work that increasingly typifies modern care.
View Article and Find Full Text PDFBackground: Mast cells are one of the characteristic factors in angiogenesis, growth, and metastatic spread of tumors. Further studies are suggested to determine the type of these cells which might be useful in the assessment of biological nature of the tumor and its future treatment modality. Few studies have evaluated mast cell infiltration in visceral tumors, especially uterine tumors.
View Article and Find Full Text PDFThe activating KIT marker plays a central role in the pathogenesis, diagnosis, and targeted treatment of systemic mastocytosis (SM). Recent studies have identified the KIT (CD117) as a marker that distinguishes nonneoplastic from neoplastic mast cells in human systemic mastocytosis. In this study, we conclude that immunohistopathology assays for KIT staining pattern are useful complimentary tools for diagnosis and evaluation of prognosis in uterus mast cell tumor (MCT) metastasis to the liver in 10 patients.
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