A Comparison of the Apical Sealing Efficacy Between Guttaflow Bioseal and Mineral Trioxide Aggregate as Root-End Filling Materials: An In Vitro Study.

Aim The objective of this study is to evaluate the efficacy of Guttaflow Bioseal (Coltene/Whaledent, Altstätten, Switzerland) in achieving an apical seal when utilized as a retrograde filling material in comparison to mineral trioxide aggregate (MTA). Methods Twenty single-rooted single-canaled human teeth were randomly allocated into two equal groups according to the used retrograde filling materials: Guttaflow Bioseal in group I and MTA in group II. The crowns were sectioned, and the root canals were prepared with rotary files and obturated (single cone technique with a resin-based sealer).