Background: The weight-adjusted-waist index (WWI) is a relatively new index to obesity. This study aimed to explore the reationship between WWI and cardiovascular disease (CVD).
Methods: This cross-sectional study included 8,899 participants aged 35 to 65 from the Ravansar non-communicable diseases (RaNCD) cohort study in Ravansar, Iran.
Background And Objectives: To assess the agreement between Anterion AS-OCT and three optical devices in measuring the white-to-white (WTW) diameter in candidates for refractive surgery.
Methods: In this cross-sectional prospective study, 129 right eyes of 129 normal individuals underwent consecutive scans with the Anterion, the Pentacam AXL, the IOLMaster 700, and the Orbscan IIz. Mean difference (MD), 95% limits of agreement (LoA), and concordance correlation coefficient (CCC) were calculated to assess agreement and interchangeability.
BMC Endocr Disord
August 2024
Background: The Lipid Accumulation Product (LAP) is a measure that indicates excessive fat accumulation in the body. LAP has been the focus of research in epidemiological studies aimed at forecasting chronic and metabolic diseases. This study aimed to evaluate the association between LAP and type 2 diabetes mellitus (T2DM) among adults in western Iran.
View Article and Find Full Text PDFThe CEPI Centralized Laboratory Network implemented key steps in the transfer and monitoring of the developed immunological SARS-CoV-2 assays to ensure standardization across all the facilities of the network. This comprehensive evaluation reinforces the reliability of the generated data and establishes a solid foundation for a standardized approach, enabling precise inter-laboratory comparisons and contributing to the overall integrity of our network's clinical results. Herein, we will provide a brief elaboration on the specific measures and procedures implemented to standardize the transfer of assays across our network.
View Article and Find Full Text PDFUnlabelled: Thoracolumbar (TL) fractures are among the most common vertebral fractures. These patients have high morbidity and mortality due to injury mechanisms and associated injuries. Spinal cord injury (SCI) is a prevalent complication of spinal fractures of the thoracolumbar region.
View Article and Find Full Text PDFBackground: Daily activities have been recommended to minimize the long-term complications of coronary artery bypass as one of the strategies to return to the normal activity level, the effectiveness of which needs further investigation. This study aims to determine the quality of life and activities of daily living one year after CABG.
Methods: This cross-sectional study was performed on 206 patients who had undergone CABG for more than one year in 2018 in the north of Iran.
To date, thousands of SARS-CoV-2 samples from many vaccine developers have been tested within the CEPI-Centralized Laboratory Network. To convert data from each clinical assay to international standard units, the WHO international standard and the CEPI standard generated by the Medicines and Healthcare products Regulatory Agency were run in multiple facilities to determine the conversion factor for each assay. Reporting results in international units advances global understanding of SARS-CoV-2 immunity and vaccine efficacy, enhancing the quality, reliability, and utility of clinical assay data.
View Article and Find Full Text PDFThe quality of drinks affects the functioning of the liver. In recent decades, the variety of high-calorie and sweet drinks has increased. The objective of this study was to explore the association between Healthy Beverage Index (HBI) and the risk of nonalcoholic fatty liver disease (NAFLD) among adults.
View Article and Find Full Text PDFBMC Gastroenterol
February 2024
Background: Accurate quantitation of immune markers is crucial for ensuring reliable assessment of vaccine efficacy against infectious diseases. This study was designed to confirm standardised performance of SARS-CoV-2 assays used to evaluate COVID-19 vaccine candidates at the initial seven laboratories (in North America, Europe, and Asia) of the Coalition for Epidemic Preparedness Innovations (CEPI) Centralized Laboratory Network (CLN).
Methods: Three ELISAs (pre-spike protein, receptor binding domain, and nucleocapsid), a microneutralisation assay (MNA), a pseudotyped virus-based neutralisation assay (PNA), and an IFN-γ T-cell ELISpot assay were developed, validated or qualified, and transferred to participating laboratories.
Interleukin-6 (IL-6) has obviously tumor-promoting and tumor-inhibitory effects and can induce an epithelial-mesenchymal transition phenotype in human breast cancer (BC) cells and implicate its potential to promote BC metastasis. Herein, we aimed to evaluate the association of variants (, , , , , , and ) with the susceptibility to BC. The databases of PubMed/Medline, Web of Science, Scopus, and Cochrane Library were searched until December 19, 2022, without any restrictions.
View Article and Find Full Text PDFBackground And Aims: Cardiopulmonary resuscitation (CPR) is referred to an attempt to maintain the respiratory system and blood circulation active to oxygenate the body's important organs until the heart and blood circulation system return to normal. CPR results are influenced by a variety of circumstances and factors. The purpose of this study was to look into the outcomes of CPR and the factors that influence them at the Dr.
View Article and Find Full Text PDFMult Scler J Exp Transl Clin
July 2023
Background: Comorbidity is a current area of interest in multiple sclerosis (MS) and is essential for multidisciplinary management. Although recent studies suggest that patients with MS have an elevated risk of developing inflammatory bowel diseases (IBD), this systematic review and meta-analysis aimed to estimate the overall risk of developing ulcerative colitis (UC), specifically in patients with MS.
Methods: In 2021, a comprehensive literature search was performed on PubMed, Scopus, Embase, and Web of Science to identify studies investigating the association between UC and MS.
Using magnetic nanoparticles (MNPs) for emulsified oil separation from wastewater is becoming increasingly widespread. This study aims to synthesize MNPs using amphiphilic coatings to stabilize the MNPs and prevent their agglomeration for efficiently breaking oil-in-water nanoemulsions. We coat two different sizes of FeO nanoparticles (15-20 and 50-100 nm) using cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS) with surfactant-to-MNP mass ratios of 0.
View Article and Find Full Text PDFGinger and its derivatives have been shown to be effective in the prevention and treatment of cancer. We undertook a systematic review to answer the question of whether ginger has a role in modifying the biomarkers of cancer in cell culture conditions and on colorectal cancer in randomized clinical trials. We performed a comprehensive search of the literature from Scopus, Embase, Web of Science, PubMed, Cochrane central register of controlled trials, and Cochrane database of systematic reviews.
View Article and Find Full Text PDFObjective: COVID-19 has recently emerged as a serious threat to global health. This study examined the laboratory investigations of patients with COVID-19, with an emphasis on liver enzymes.
Methods: This retrospective, single-center study was performed on patients with COVID-19 who were admitted to Imam Reza Hospital, Iran from March 2020 to February 2021.
J Cataract Refract Surg
October 2022
Purpose: To assess the associations of angle κ and Pentacam decentration indices with elevation maps in normal refractive surgery candidates.
Setting: Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran.
Design: Retrospective observational study.
The response to the demand for biomedical testing on small volumes of biofluids has led to a range of new microsampling devices and related techniques. Simple cost-effective sampling devices are available, but most do not incorporate sample clean-up and necessitate extensive sample processing by the analyst. To address both cleanup and analyte stability, a porous polymeric thin film made of methacrylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) coated (5 × 18 mm) on a stainless steel substrate was used for the extraction of seven tricyclic antidepressants (TCAs) from plasma spots, with analysis by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
View Article and Find Full Text PDFAn efficient analytical method is developed using a porous sorptive polymer for thin film microextraction (PSP-TFME) of 8 model drugs from human urine samples. The analysis is conducted with ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). The composition of the porous extraction phase, prepared on a stainless steel substrate, has been optimized for basic drugs of abuse and comprises methacrylic acid (MMA) as the monomer and ethylene glycol methacrylate (EGDMA) as the crosslinker.
View Article and Find Full Text PDFTissue engineering is biomedical engineering that uses suitable biochemical and physicochemical factors to assemble functional constructs that restore or improve damaged tissues. Recently, cell therapies as a subset of tissue engineering have been very promising in the treatment of ocular diseases. One of the most important biophysical factors to make this happen is noninvasive electrical stimulation (ES) to target ocular cells that may preserve vision in multiple retinal and optic nerve diseases.
View Article and Find Full Text PDFMolecularly imprinted polymers (MIPs) have become an important class of materials for selective and efficient adsorption of target analytes. Despite versatility of MIPs for fabrication in numerous formats, these materials have been primarily reported as solid phase extraction packing materials. An effective thin film MIP prepared on stainless steel substrate is reported here for high throughput enrichment of organophosphorus pesticides (OPPs) from water and beverage samples followed by liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis.
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