The Protective Effects of Pyridoxine on Linezolid-Induced Hematological Toxicity, Hepatotoxicity, and Oxidative Stress in Rats.

Objective: Linezolid is often used to treat antibacterial-resistant infections. Linezolid can cause side effects. To date, the effectiveness of the simultaneous administration of pyridoxine and linezolid is unclear.

Transconjunctival Approach: A Safe and Effective Access to Mass Lesions in the Anterior Orbit.

Background: The orbit is an eloquent organ of the body. Safe surgical access to the orbit could be challenging due to the dense network of critical structures confined to it. There are versatile approaches to different parts of the orbit that could be used by neurosurgeons without causing injury to critical neurovascular structures.

Choroidal osteoma in a preterm infant.

Choroidal osteoma (CO) is a rare, benign, and usually unilateral intraocular tumor composed of mature bone affecting the choroid. It appears as slightly elevated, yellowish-white, or orange choroidal mass with well-defined borders. It is commonly encountered in young female adults.

WIDE-FIELD SMARTPHONE FUNDUS VIDEO CAMERA BASED ON MINIATURIZED INDIRECT OPHTHALMOSCOPY.

Purpose: This study is to develop a low-cost, easy-to-use, wide-field smartphone fundus video camera to enable affordable point-of-care examination and telemedicine.

Methods: The wide-field smartphone fundus camera is based on a unique design of miniaturized indirect ophthalmoscopy. For proof-of-concept prototype, we used a Samsung Galaxy S6 smartphone and all off-the-shelf components.

Evaluation of Aflibercept Treatment Responses in Eyes with Bevacizumab/Ranibizumab-resistant Wet Age-related Macular Degeneration.

Objectives: To evaluate anatomic and functional results after switching from intravitreal bevacizumab or ranibizumab treatment to aflibercept for wet (neovascular) age-related macular degeneration.

Materials And Methods: This retrospective study included 22 eyes of 22 patients resistant to treatment with at least 6 injections of bevacizumab or ranibizumab. The first three injections had been applied monthly, the others pro re nata (PRN).

Quantitative Scheimpflug camera study of the lens density in healthy Turkish population.

The purpose of this study is to evaluate the association between the age and the density of anterior, posterior, and nuclear parts of lens and detect the normal lens density (LD) values in different age groups. 370 eyes of 370 voluntary healthy Turkish subjects were included. These were divided in four groups according to their age.

Evaluation of the long-term results of trabectome surgery.

The aim of this study was to investigate the safety and efficacy of ab interno trabeculectomy which is a minimally invasive glaucoma surgery, in the late period, performed via trabectome instrument. A total of 70 eyes followed up with a diagnosis of open-angle glaucoma (OAG) and undertaken trabectome surgery were included in the study. Preoperative and postoperative intraocular pressures (IOPs), number of the drugs used, and complications were retrospectively investigated and the data were evaluated.

Prolidase Enzyme Activity in Conjunctiva and Pterygium Tissues.

Background: The aim of this study was to determine prolidase activity in conjunctival tissue and its relationship with pterygium.

Material And Methods: Prolidase activity was measured in 23 pterygium and 25 healthy conjunctival tissues and the 2 groups were compared.

Results: Prolidase enzyme activity could not be measured in either the healthy conjunctival or in pterygium tissues.

The protective effect of Capparis ovata on 6-mercaptopurine-induced hepatotoxicity and oxidative stress in rats.

Capparis ovata is a member of Capparidacaeae family has been used in phytomedicine with a lot of positive effects such as an antioxidative, antihyperlipidemic, anti-inflammatory, and antihepatotoxic agent. The aim of this study was to research the protective effect of C. ovata on 6-mercaptopurine (6-MP) induced to hepatotoxicity and oxidative stress in rats.

The effect of chronic smoking on lens density in young adults.

Purpose: To investigate the effect of chronic cigarette smoking on lens density by Pentacam HR lens densitometry in young adults.

Methods: Sixty chronic smokers who smoked at least 10 cigarettes per day for at least 2 years and 60 age- and sex-matched healthy control subjects were included in this prospective cross-sectional, comparative study. Presence of an ocular or systemic disease that might affect lens were determined as exclusion criteria.

Influence of hyperbaric oxygen therapy on central corneal thickness.

Background/aims: Hyperbaric oxygen (HBO) therapy is used in the treatment of several disorders. Little is known about the effects of HBO treatment on corneal thickness. The aim of this study was to investigate the effect of HBO treatment on central corneal thickness.

Intracameral Perfluoropropane (C(3)F(8)) Gas in the Repair of Extensive Descemet's Membrane Detachment During Phacoemulsification Surgery.

Descemet's membrane detachment (DMD) is one of the rare complications seen during or after cataract surgery. It can cause permanent corneal decompensation if untreated or not reattached spontaneously. A patient with an extensive DMD (involving approximately upper two-thirds of the cornea) during uncomplicated phacoemulsification surgery is reported.

Autofluorescence findings in Vogt-Koyanagi-Harada disease.

Purpose: To report shortwave autofluorescence (SW-AF) and near infrared autofluorescence (NIR-AF) findings in a case of Vogt-Koyanagi-Harada (VKH) disease.

Methods: A 22-year-old man presented with a 2-week history of headache, moderate hearing loss, discolored hair, and bilateral gradually decreased vision (20/800 bilaterally). Ophthalmologic examinations revealed bilateral granulomatous anterior uveitis and multiple patchy bullous retinal detachments.

Hemicentral retinal artery occlusion in a breast cancer patient using anastrozole.

Background: Anastrozole, an aromatase inhibitor, is commonly used in the adjuvant treatment of breast cancer. Anastrozole treatment is associated with a risk of thromboembolic events and retinal vascular side effects. Herein, we present a case of hemi-central retinal artery occlusion diagnosed in a breast cancer patient using anastrozole.

Carbon monoxide-induced cortical visual loss: treatment with hyperbaric oxygen four years later.

Objective: We present a patient who developed visual loss after carbon monoxide (CO) poisoning and was treated with hyperbaric oxygen.

Clinical Presentation And Intervention: A 21-year-old woman poisoned with CO (with coma lasting 4 h and carboxyhemoglobin level 46%) developed seizures and cortical blindness 3 days after poisoning. Four years later, her visual acuity was 0.

Fundus autofluorescence in choroidal rupture.

Purpose: To investigate fundus autofluorescence (FAF) imaging findings for patients with choroidal rupture.

Methods: FAF images were recorded with a new-generation confocal scanning laser ophthalmoscope. Three patients with choroid ruptures, one acute and two chronic, were included in the study.

Validation of the ocular trauma score for intraocular foreign bodies in deadly weapon-related open-globe injuries.

Background And Objective: To evaluate the prognostic value of the Ocular Trauma Score (OTS) in cases of deadly weapon-related open-globe injuries with intraocular foreign bodies.

Patients And Methods: A retrospective, interventional case series included 20 eyes of 20 patients who had deadly weapon-related open-globe injuries with intraocular foreign bodies. The OTS was calculated for each patient by adding the determined numbers of OTS variables at presentation (initial visual acuity, rupture, endophthalmitis, perforating injury, retinal detachment, and afferent pupillary defect).