Publications by authors named "Ali Ata Tuz"

Neutrophils are indispensable for defense against pathogens. Injured tissue-infiltrated neutrophils can establish a niche of chronic inflammation and promote degeneration. Studies investigated transcriptome of single-infiltrated neutrophils which could misinterpret molecular states of these post mitotic cells.

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Article Synopsis
  • Autonomous migration is crucial for immune cell function and has significant implications for various diseases.
  • ComplexEye is a new high-throughput microscope that allows for efficient analysis of cell migration in standard 96- and 384-well plates.
  • This system dramatically speeds up the process of screening for compounds that affect neutrophil migration, completing in 4 days what would typically take 60 days with standard methods.
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Article Synopsis
  • Light-sheet fluorescence microscopy (LSFM) is effective for high-resolution imaging of tissue vasculature but faces challenges with labor-intensive data processing due to large datasets.!* -
  • VesselExpress is a new automated software that analyzes key vascular network parameters quickly and efficiently, being around 100 times faster than existing tools and requiring no user input.!* -
  • The software uses a unique dual Frangi filter approach to reveal significant changes in brain vasculature due to obesity and highlights distinct 3D vascular differences across various organs.!*
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Objective: The aim of this study was to determine the prevalence and the characteristics of coronavirus disease 2019 (COVID-19) in a tertiary outpatient clinic of asthma patients, find the predisposing asthma phenotype to COVID-19, and to see their adherence to asthma treatment.

Material And Methods: A retrospective, cross-sectional, real life study was conducted via phone interviews with the patients being followed in the asthma outpatient clinic. From the files of the patient information was obtained about their demographics, asthma phenotype, co-morbidity, prick tests, spirometry test results and their medications at the last visit before the COVID-19 pandemic.

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