Background: Epidemiological studies have shown varying prevalence rates of dental anomalies worldwide, ranging from 5.2% to 56.9%, with a higher rate of 90.
View Article and Find Full Text PDFAccurate determination of glutathione (GSH) in food supplements and human biological fluids is critical for preventing disorders related to GSH imbalances. To address this, a selective and sensitive fluorometric method was developed for GSH detection using nickel nanoclusters functionalized with polyvinylpyrrolidone (PVP) and 4-mercaptobenzoic acid (4-MBA) (PVP/4-MBA@Ni NCs). In this system, PVP serves as the stabilizer, while 4-MBA functions as both a stabilizer and reducing agent.
View Article and Find Full Text PDFBackground: Stroke is a significant contributor to both mortality and compromised physical function. Endovascular thrombectomy (EVT) is now the recognized standard of care for anterior circulation acute ischemic stroke (AIS) with large vessel occlusion (LVO), especially when favorable brain images are evident within 24 h of symptom onset. This study elucidated the characteristics, clinical profiles, and outcomes of patients who underwent EVT for AIS.
View Article and Find Full Text PDFSpec Care Dentist
December 2024
Sturge-Weber syndrome (SWS) or encephalotrigeminal angiomatosis is a rare congenital disorder that affects the skin, brain, and eye. It is characterized by facial port-wine stains, leptomeningeal angiomas, and glaucoma. SWS can also cause neurological complications, such as seizures, headaches, cognitive impairment, and stroke.
View Article and Find Full Text PDFAn electrochemical sensing approach was developed for the detection of the agricultural antibiotic drug kasugamycin. The method involves the construction of an electrochemical sensor comprising molecularly imprinted polymers (MIPs) embedded within a carbon paste (CP) matrix. The MIPs are designed to have imprinted sites that match the size and geometry of the Cu(II)-kasugamycin coordinated complex.
View Article and Find Full Text PDFDrought stress severely affects crop productivity and threatens food security. As current trends of global warming are predicted to exacerbate droughts, developing drought-resilient crops becomes urgent. Here, we used the drought-tolerant (BW35695) and drought-sensitive (BW4074) wheat varieties to investigate the physiological, biochemical, and leaf proteome responses underpinning drought tolerance.
View Article and Find Full Text PDFBackground: Pituitary stalk interruption syndrome is a rare congenital anomaly of the pituitary gland characterized by growth hormones deficiency (with or without other pituitary hormone deficiencies) along with radiological features of a thin or interrupted pituitary stalk, an ectopic or absent posterior pituitary, or a hypoplastic or absent anterior pituitary.
Case Presentation: A 10-year-old baby boy came with short stature. The laboratory investigations were done and showed low growth hormones and low thyroid-stimulating hormone.
Background: The term "cellulitis" is frequently used to describe a non-necrotizing inflammation of the skin and subcutaneous tissues that is typically caused by an acute infection and does not affect the muscles or fascia. Warmth, erythema, tenderness, swelling, and localized pain are the hallmarks of cellulitis. Life-threatening and debilitating outcomes from cellulitis include necrotizing fasciitis, necrotizing hypodermitis, abscess formation, septic shock, and, in extreme cases, death.
View Article and Find Full Text PDFResidual drifts are an important measure of post-earthquake functionality in bridges and buildings, and can determine whether the structure remains fit for its intended purpose or not. This study aims at investigating numerically, through finite element (FE) analysis in ABAQUS, the cyclic response of exterior steel I beam-hollow column connection using welded shape memory alloys (SMA) bolts and seat angles. This is followed by validating the numerical model using an accredited experimental data available in the literature through different techniques, (1) SMA bolts, (2) SMA angles, (3) SMA bolts and angles.
View Article and Find Full Text PDFBACKGROUND Modification of the glass fiber post (GFP) with titanium dioxide or silver particles can improve the durability and reliability of dental treatments for ensuring long-term success. This research assessed the tensile bond strength (TBS) of an adhesive system used for cementing GFPs into root dentin following the incorporation of nanoparticles of titanium dioxide (NTiO2) and silver (NAg). MATERIAL AND METHODS Sixty human maxillary canines were prepared to create a 10-mm intra-radicular space for post placement from the cementoenamel junction.
View Article and Find Full Text PDFStroke is a predominant contributor to global mortality and disability and represents a complex and heterogeneous disease characterized by diverse risk factors and clinical presentations. The likelihood of stroke patients being at risk of a second stroke within the first five years is higher, especially within the initial two weeks. The distressing prospect of experiencing recurrent stroke shortly after reperfusion therapy adds an additional layer of complexity, potentially reversing prior progress.
View Article and Find Full Text PDFAim To examine unexplored knowledge of cardiovascular highrisk medications and perception thereof among practising nurses and students in the Kingdom of Saudi Arabia (KSA). Methods The multicentre cross-sectional quantitative study used an online survey dichotomised into a knowledge test (true/false and multiple choice questions) and a perception assessment (closed-ended questions). Four hundred and eighteen nurses participated in the study.
View Article and Find Full Text PDFA novel electrochemical sensor with a dual-template molecular imprinting technology was fabricated for the simultaneous detection of paracetamol (PAR) and isoniazid (INZ). The sensor was constructed using nitrogen and sulfur co-doped molybdenum carbide (N, S@MoC) and a thin layer of electro-polymerized methylene blue was applied onto the surface of the N, S@MoC. The electrochemical sensor demonstrated remarkable analytical efficiency for the concurrent PAR and INZ quantification under optimal circumstances.
View Article and Find Full Text PDFPLoS One
January 2024
Background: Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in patients with sepsis. However, multiple clinical and laboratory parameters indicate impending sepsis and organ dysfunction.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
April 2024
Evidence reveals that people with mental illnesses have a greater risk of experiencing oral diseases such as dry mouth and dental caries and have greater oral treatment needs. This is related to multifactorial causes such as factors related to the condition itself, symptoms, side effects of polypharmacy, and a lack of accessibility to dental services. This article aims to provide a summary of the reported prevalence of the most common mental illnesses in Saudi Arabia (SA), such as schizophrenia, obsessive-compulsive disorder (OCD), bipolar disorders, and dementia.
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