Homology groups in CR-warped products of complex space forms.

In the present paper, by using the result of Lawson-Simons [15], we adopt a different technique to show that there are no stable integral -currents and a non-trivial homology group in a compact oriented CR-warped product submanifold in a complex space forms space by imposing some restrictions on the squared norm of gradient and the Laplacian of warped function. Finally, we show that the same approach can be given by using Dirichlet energy, positive eigenvalue, and Hamiltonian.

Optical impressions assessment for overlay restorations with rubber dam: A clinical trial.

Objective: The possibility of making impressions of teeth prepared with a rubber dam in place has been proposed; however, this requires trimming and rescanning the mesh, which has been described as a cause of accuracy loss. This study aims to clinically determine whether overlay restorations obtained from a scan with a rubber dam in place have equivalent marginal fit, contact points, and occlusal fit to the same type of restorations obtained from a scan without a rubber dam.

Material And Methods: Thirty patients who underwent overlay restoration of a molar with at least one neighbouring tooth were selected.

Exploring quantum computational, molecular docking, and molecular dynamics simulation with MMGBSA studies of ethyl-2-amino-4-methyl thiophene-3-carboxylate.

2-aminothiophenes derivative, Ethyl-2-amino-4-methyl thiophene-3-carboxylate (EAMC) has been synthesized, characterized, and investigated quantum chemically. It was experimentally investigated by different spectroscopic methods like- NMR (H-NMR and C-NMR), FT-IR, and UV-Visible. B3LYP method and 6-311++G(d,p) basis set were employed for optimization of molecular structure and calculation of wave numbers of normal modes of vibrations and various other important parameters.

Dynamical phenomena developed by a spiralling stretchable sheet in magnetized Casson-spinel ferrite nanofluid.

Nanofluid research has sparked widespread attention due to its immense implementations in various courses, including chemical engineering, microelectronics, solar energy, cooling systems, electronics, power-saving, etc. This research offers modelling and numerical simulation for the magnetized Casson-based spinel ferrite (MnFeO) nanofluid stream owing to a spiralling stretchable sheet placed in a Darcy permeable medium. Diverse impacts like nonlinear heat radiation, viscous and Joule warms, and heat generation/absorption are considered in stimulating heat exchange.

Cutting Edge: Negative Regulation of Inflammasome Activation by TRAF1 Can Limit Gout.

Secretion of IL-1β, a potent cytokine that plays a key role in gout pathogenesis, is regulated by inflammasomes. TRAF1 has been linked to heightened risk to inflammatory arthritis. In this article, we show that TRAF1 negatively regulates inflammasome activation to limit caspase-1 and IL-1β secretion in human and mouse macrophages.

Survival outcomes for patients with nasopharyngeal carcinoma in non-endemic region in the UK treated with intensity modulated based radiotherapy 65 Gy in 30 fractions ± weekly cisplatin chemotherapy.

Background: Nasopharyngeal carcinoma (NPC) is rare in the UK. The aim of the current study was to investigate survival outcomes for patients with NPC treated with (chemo)radiotherapy using 65 Gy in 30 fractions in a non-endemic region.

Materials And Methods: All consecutive 62 patients with histology proven non-metastatic nasopharyngeal carcinoma diagnosed between January 2009 to June 2019 were included in this retrospective analysis.

Iron(III) Complexes of a Hexadentate Thioether-Appended 2-Aminophenol Ligand: Redox-Driven Spin State Switchover.

A green complex [Fe(L)] (), supported by the deprotonated form of a hexadentate noninnocent redox-active thioether-appended 2-aminophenolate ligand (HL = ,'-bis(2-hydroxy-3,5-di--butylphenyl)-2,2'-diamino(diphenyldithio)ethane), has been synthesized and structurally characterized at 100(2) K and 298(2) K. In CHCl, displays two oxidative and a reductive one-electron redox processes at values of -0.52 and 0.

Detection of ASC Oligomerization by Western Blotting.

Apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) is an adaptor protein that is essential for the activation of several inflammasome complexes. Activation of inflammasomes leads to pathogenic clearance and inflammatory cell death called pyroptosis. Upon inflammasome activation, ASC oligomerization leads to the recruitment and activation of caspase-1, which in turn converts pro-inflammatory cytokines (e.

A Rare Case of Hypoparathyroidism and Myxedema Coma in a Patient With Diamond-Blackfan Anemia.

Diamond-Blackfan anemia (DBA) is a rare genetic condition that presents due to bone marrow failure caused by a dysfunction in ribosomal biogenesis and function. The patients would often require chronic transfusions as treatment, which puts them at high risk for the development of secondary hemochromatosis. This secondary hemochromatosis results in endocrinopathies due to iron deposition into the endocrine glands.

Bronchial Thermoplasty in Patients with Severe Persistent Asthma: A Literature Review.

The literature review aimed to see the safety and efficacy of bronchial thermoplasty in patients with severe asthma. We searched the online database, PUBMED, using bronchial thermoplasty and asthma as the key words and including trials from 2007 to 2021. Our review found that bronchial thermoplasty reduces asthma-related hospitalizations, emergency room visits and asthma exacerbations with sustained benefits for 5-10 years.

Solitary Fibrous Tumors of the Pleura.

Solitary fibrous tumors of the pleura (SFTP) are rare neoplasms. We present a case of a 53-year-old female presenting to the pulmonary clinic after an incidental finding of a right-sided chest wall tumor on a chest X-ray. A CT scan of the chest showed a pleural-based right upper lung mass; a biopsy of the mass was consistent with a solitary fibrous tumor.

Guided tooth preparation device fabricated with a complete digital workflow: A dental technique.

Guided tooth preparations allow clinicians to provide fixed dental prostheses for dentate patients in an efficient manner. One approach uses a digital preparation device technique where the preparation of a tooth needing a crown is guided by a device. Compared with conventional techniques, this method allows for accurate abutment preparation more efficiently and with improved quality.

Recent applications of Rose Bengal catalysis in N-heterocycles: a short review.

The visible light harnessing ability of Rose Bengal, an organic dye, has been extensively employed in organic chemistry over the last few years. In visible light mediated reactions, this photoredox catalyst operates through multiple pathways and has the ability to provide distinctly different and valuable results. The most significant of these results are bond creation, bond functionalization, particularly for C-H and C-heteroatom bonds, and cross couplings.

Innate immunity drives pathogenesis of rheumatoid arthritis.

Rheumatoid arthritis (RA) is an autoimmune disease affecting ∼1% of the general population. This disease is characterized by persistent articular inflammation and joint damage driven by the proliferating synovial tissue fibroblasts as well as neutrophil, monocyte and lymphocyte trafficking into the synovium. The factors leading to RA pathogenesis remain poorly elucidated although genetic and environmental factors have been proposed to be the main contributors to RA.

Abiraterone acetate plus Prednisone/Prednisolone compared with Enzalutamide in metastatic castration resistant prostate cancer before or after chemotherapy: A retrospective study of real-world data (ACES).

Background: Abiraterone acetate combined with Prednisone/Prednisolone (AA+P) and Enzalutamide (ENZ) have proven survival benefit in men with metastatic castration-resistant prostate cancer (mCRPC) in chemotherapy-naïve and prior chemotherapy patients. There have been no studies directly comparing the effectiveness of ENZ to AA+P in mCRPC patients.

Methods: A retrospective, survival analysis study of 143 real-world mCRPC patients (90 in AA+P and 53 in ENZ group) was conducted.

Diffusion and spillover effects of an evidence-based mental health intervention among peers and caregivers of high risk youth in Sierra Leone: study protocol.

Background: Evidence-based mental health interventions have helped address health services gaps, but their reach and societal benefit can be limited in low resource settings. The current study extends an ongoing scale-up study of a cognitive behavioral therapy (CBT)-based intervention, the Youth Readiness Intervention (YRI), among high risk youth in post-conflict Sierra Leone to investigate mechanisms of diffusion and spillover effects of the YRI among peers and caregivers of youth who receive the intervention.

Methods: We will recruit and enroll YRI index participants and control index participants (ages 18-30).

Immediately loaded interim complete-arch implant-supported fixed dental prostheses fabricated with a completely digital workflow: A clinical technique.

A digital method for delivering an immediately loaded interim complete-arch implant-supported prosthesis is described. Reference pins were used to accurately superimpose a postoperative scan with the scan bodies in place on a preoperative scan with the framework design, including the interocclusal relationship and the occlusal scheme. A prefabricated auxiliary device was used after surgery to record the position of the implants and after scanning to obtain an accurate transfer of the implant positions by means of a free software program, allowing an excellent fit of the fabricated prosthesis.

: An Open-Source Wireless Hardware and Software Platform for Building Energy and Indoor Environmental Monitoring and Control.

This work demonstrates an open-source hardware and software platform for monitoring the performance of buildings, called , that is designed to provide data on indoor environmental quality, energy usage, HVAC operation, and other factors to its users. It combines: (i) custom printed circuit boards (PCBs) with RFM69 frequency shift keying (FSK) radio frequency (RF) transceivers for wireless sensors, control nodes, and USB gateway, (ii) a Raspberry Pi 3B with custom firmware acting as either a centralized or distributed backhaul, and (iii) a custom dockerized application for the backend called that serves as the director software managing message brokering via Message Queuing Telemetry Transport (MQTT) protocol using VerneMQ, database storage using InfluxDB, and data visualization using Grafana. The platform is built around the idea of a private, secure, and open technology for the built environment.

Crystal structure of 4-[(3-meth-oxy-2-oxidobenzyl-idene)azaniumyl]-benzoic acid methanol monosolvate.

In the crystal of the title compound, CHNO·CHOH, the Schiff base mol-ecule exists in the zwitterionic form; an intra-molecular N-H⋯O hydrogen bond stabilizes the mol-ecular structure. The benzene rings are nearly co-planar, subtending a dihedral angle of 5.34 (2)°.

Spontaneous Right Coronary Artery Dissection In A Normotensive Post-Partum Female.

Acute myocardial infarction following coronary artery dissection during the post-partum period is a rare entity. Greater hemodynamic stress and hormonal changes increase the risk of developing a coronary artery dissection post-partum. Herein, we report the first case of a normotensive patient from Pakistan that presented with inferior wall myocardial infarction following 10-days postpartum due to right coronary artery dissection.

Ceftazidime-Resistant Burkholderia Cepacia: An Unusual Case in a Pregnant Patient.

Intensive care unit (ICU) sepsis in patients is a common clinical practice primarily in the tertiary care settings. Multidrug resistance to pathogens causing ICU sepsis is widespread, and it poses a severe threat to physicians in terms of managing their patients. At times, physicians get exposed to a pathogen they have never encountered before.

Comparison of postoperative pain after root canal treatment using reciprocating instruments based on operator's experience: A prospective clinical study.

Background: The aim of the present study was to compare clinically the incidence of postoperative pain after endodontic treatment using the Reciproc System, taking into account the operator's experience.

Material And Methods: One hundred patients scheduled for routine endodontic treatment were enrolled in this study. Endodontic treatment was carried out in a single visit by undergraduate and postgraduate students.

Crystal structure of (2,2'-bi-pyridine-κ,')bis-(3,5-di--butyl--benzo-quinonato-κ,')ruthenium(II).

In the title mononuclear complex, [Ru(CHO)(CHN)], the Ru ion has a distorted octa-hedral coordination environment defined by two N atoms of the chelating 2,2'-bi-pyridine ligand and four O atoms from two 3,5-di--butyl-benzo-quinone ligands. In the crystal, the complex mol-ecules are linked by inter-molecular C-H⋯O hydrogen bonds and π-π stacking inter-actions between the 2,2'-bi-pyridine ligands [centroid-centroid distance = 3.538 (3) Å], resulting in a layer structure extending parallel to the plane.