Publications by authors named "Ali A Esmaeili"

Background: Toxoplasma gondii (T. gondii) is the most successful obligate protozoan that can infect warm-blooded vertebrate hosts. Some researchers suggest that the presence of Toxoplasma cysts in the brain can lead to mental disorders.

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Article Synopsis
  • A study was conducted to find out how common thyroid dysfunction is among older Iranian adults aged 60 and over, using data from a cohort of 363 people.
  • The researchers measured hormone levels and classified participants into groups based on their thyroid function, discovering that 23.97% displayed some form of thyroid dysfunction, mainly hypothyroidism, with a notable prevalence in women.
  • The findings suggest a significant number of older adults in Iran have thyroid issues, particularly subclinical hypothyroidism, indicating a need for more research in this area.
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Background: There is evidence of the role of vitamin D deficiency in cognitive decline. However, the results of studies regarding the relationship between the reduction of vitamin D concentrations and cognitive impairment are heterogeneous.

Objectives: We aimed to answer the question of whether vitamin D deficiency is associated with cognitive decline in older adults.

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Background And Aim: Mental disorders are among the most common diseases in the world. Not only the lack of social support and health services but also the social stigma surrounding individuals with mental disorders and their family members has exacerbated the difficulty of living with and caring for these patients. The present study aimed to determine the effect of group psychological training on the attitudes of family caregivers taking care of patients with schizophrenia as a common mental disorder.

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The tumor microenvironment is composed of heterogeneous populations of cells, including cancer, immune, and stromal cells. Progression of tumor growth and initiation of metastasis is critically dependent on the reciprocal interactions between cancer cells and stroma. Through RNA-Seq and protein analyses, we found that cancer-associated fibroblasts derived from human breast cancer brain metastasis express significantly higher levels of chemokines CXCL12 and CXCL16 than fibroblasts from primary breast tumors or normal breast.

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