An evaluation of the SureID 23comp Human Identification Kit for kinship testing.

Short tandem repeat (STR) profiling has been routinely used in kinship testing since the introduction of commercial kits in the mid-1990s. While 15 to 23 STR loci normally give definitive results in simple kinship testing, additional loci are sometimes required to resolve complex cases. The SureID 23comp Human Identification Kit, recently released by Health Gene Technologies (China), multiplexes amelogenin and 22 autosomal STRs, 17 of which are non-CODIS STRs.

Potential activity of the purine compounds caffeine and aminophylline on bacteria.

Background: Purine compounds are special types of alkaloids. Caffeine and aminophylline are considered the most important members of purines due to their wide use in therapeutics.

Aims: To detect any potential antibacterial effects on pathogenic bacteria of the widely prescribed members of purines caffeine and aminophylline.

Determination of antidermatophytic effects of non-steroidal anti-inflammatory drugs on Trichophyton mentagrophytes and Epidermophyton floccosum.

Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most common pharmacological agents. They have three primary therapeutic properties including anti-inflammatory, anti-pyretic and analgesic effects. Seven NSAIDs were tested against two species of dermatophytes.

Elevation of antidermatophytic action of mefenamic acid by cobalt ions.

Objectives: To evaluate the antifungal property of mefenamic acid, which is a member of non-steroidal anti-inflammatory drugs (NSAIDs) group.

Materials And Methods: In order to evaluate the antifungal property of mefenamic acid on dermatophytes, it was mixed with cobalt (Co) in culture media. Two species related to two genera of dermatophytes were tested for their susceptibility to mefenamic acid and its complex with Co by using colony diameter measurement method.

In vitro antibacterial activity of Ibuprofen and acetaminophen.

Background: Ibuprofen and acetaminophen are common chemical agents that have anti-inflammatory, antipyretic, and analgesic activity.

Aims: To detect any potential antibacterial effects of ibuprofen and acetaminophen on pathogenic bacteria.

Materials And Methods: Ibuprofen and acetaminophen were tested for antibacterial activity against seven isolates of bacteria including gram positive bacteria (Staphylococci aureus and Bacillus subtilis) and gram negative bacteria (E.

Synergistic properties of methylxanthine with cadmium and mercury on dermatophytes.

Background: Methylxanthine has many antimicrobial effects on different types of organisms. Synergism actions between methylxanthine and cadmium or mercury on dermatophytes were tested.

Aims: To determine the synergistic property between methylxanthine and cadmium or mercury on the growth of dermatophytes.

Toxic effect of heavy metals on dermatophytes.

For determining the toxic effect of heavy metals on dermatophytes, eight heavy metals were tested using colony diameter method. Cadmium showed high toxicity effects on isolated fungi at minimal inhibitory concentration of 27 μg ml(-1) for Trichophyton mentagrophytes and of 20 μg ml(-1) for Epidermophyton floccosum, while iron enhanced dermatophytic growth. Other heavy metals revealed variable effect on isolated fungi.