Publications by authors named "Ali İlker Filiz"

Background: Uncertainty raises questions in kidney transplant during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic regarding the recipient, the donor, and health care professionals. The pandemic not only has disrupted kidney transplanted patients but also has influenced transplant systems, donation chains, and timely and safe transplant surgeries. In the present study, we aimed to explore the global effects of the SARS-CoV-2 pandemic on kidney transplant.

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  • - The study compared the effects of once-daily (TAC-OD) versus twice-daily (TAC-BID) tacrolimus formulations in newly transplanted kidney patients to assess efficiency and graft function.
  • - Results showed that TAC-OD required a higher initial dosage and had greater fluctuations in blood concentration during the first month, but both formulations resulted in similar outcomes regarding kidney function.
  • - The conclusion suggests that while TAC-OD may need higher doses early on, it is just as effective as TAC-BID in the short term for kidney transplant recipients.
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Purpose: The COVID-19 pandemic brought unprecedented conditions for overall health care systems by restricting resources for non-COVID-19 patients. As the burden of the disease escalates, routine elective surgeries are being cancelled. The aim of this paper was to provide a guideline for management of endocrine surgical disorders during a pandemic.

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Objectives: Setting up and advocating a thesis is mandatory at the end of the residency training program to become a specialist in general surgery according to the regulations on medical specialization in Turkey. Writing a thesis helps the resident to learn to ask structured questions, assembling the most accurate study design, managing the study process, collecting the results and building a conclusion with medical implications. In this descriptive study, we aimed to investigate the publication rates of the theses written in the field of general surgery and to assess the properties of the published theses.

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Objectives: The renal transplant program of Istanbul Okan University Hospital started in August 2017. Five cadaveric and 95 living donor kidney transplants have been performed for over 16 months. In this study, we aimed to share our experiences regarding kidney transplantation.

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Purpose: Many studies evaluating the effect of intragastric botulinum toxin type A injection (IG-BTxA) for the treatment of obesity have been published. However, none of these studies combined this procedure with a calorie-restricting high-protein diet. Herein, we aimed to evaluate the effects of IG-BTxA application combined with a calorie-restricting high-protein diet.

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Castleman's disease (CD) is a lymphoproliferative disorder and the occurrence of CD in the small bowel is rare. In this study, we present one case of CD causing mechanical intestinal obstruction due to involvement of terminal ileum. A 50-year-old man was admitted to the hospital with signs and symptoms of mechanical intestinal obstruction without history previous surgery.

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  • The study compares the effects of krill oil (KO) and fish oil (FO) on wound healing in a rat model after colon surgery, highlighting differences in fatty acid composition between the two oils.
  • A total of 42 male rats were used, divided into groups receiving either oil or serving as controls, with various assessments conducted on days 3 and 7 post-surgery.
  • Results showed that the KO group had significantly better outcomes in measures such as tissue integrity and healing indicators compared to the FO group, suggesting KO may be the superior omega-3 source for reducing postoperative complications.
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Background: The staple line leakage is a dangerous complication of sleeve gastrectomy. Various strategies have been tried to reduce the leakage risk. The amniotic membrane (AmM) is the inner layer of the placental membranes and has anti-inflammatory, anti-fibrosis, and anti-scarring effects, and it also has lower immune characteristics which are another essential characteristic of AmM concerning its utility for grafting.

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  • The study aimed to compare the quality and accuracy of sleeve gastrectomy videos available on WebSurg® and YouTube®.
  • The method involved evaluating the most viewed videos on both platforms using established scoring systems for educational and technical quality.
  • Results showed that WebSurg® videos generally scored higher in educational accuracy compared to YouTube® videos, but both platforms lacked comprehensive information on preoperative and postoperative processes.
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  • - Our study compared three surgical methods for treating sacrococcygeal pilonidal sinus disease: Limberg transposition flap, Karydakis flap, and primary closure, using data from 634 patients over two years.
  • - We found that while there were no significant differences in patient demographics, primary closure had the shortest operative time and hospital stay, but a higher recurrence rate.
  • - The Karydakis flap showed fewer early surgical complications compared to the other methods, highlighting its effectiveness in reducing postoperative issues.
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  • - The study explored how geographical differences impact the clinical presentation and surgical outcomes of patients with primary hyperparathyroidism (pHPT) across three regions: Black Sea, Mediterranean, and Anatolia.
  • - Data from 694 patients across 23 centers indicated that the median age was 54, with 25% being asymptomatic; significant variations emerged in preoperative symptoms, serum calcium levels, and adenoma sizes depending on the region.
  • - Findings suggest that environmental factors related to different habitats influence the clinicopathological characteristics of pHPT patients, with South-East Anatolia showing all symptomatic patients, while Bulgaria had the largest adenoma sizes and highest calcium levels.
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Objective: Colon cancer patients presented with obstruction were known to have worse postoperative morbidity and mortality rates, but conflicting data has been reported in recent years. We aimed to investigate postoperative complication rates, and short and long-term oncological outcomes in patients with colon cancer treated with either emergency surgery due to obstruction or elective surgery.

Methods: Two hundred fifty two patients were analyzed.

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Hemorrhoidectomy is used for the surgical treatment of high-grade hemorrhoids. The most prominent complaint after hemorrhoidectomy is pain. Postoperative pain management is still a big problem after surgery in patients with hemorrhoidectomy.

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Introduction: Early diagnosis of acute appendicitis, known as the most frequent cause of acute surgical abdominal pathologies, dramatically decreases the related complications. D-lactate, produced by intestinal bacteria as a fermentation product, may be useful in diagnosing acute abdominal pathologies. The aim of this study was to investigate whether the presence of d-lactate would be a significant indicator in the early diagnosis of acute appendicitis.

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Objective: The intent of our study was to compare the effects of dexmedetomidine versus midazolam on perioperative hemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy.

Material And Methods: A total of 60 ASA I-II patients, between 20 and 80 years of age were included in the study. Patients were randomly assigned to two groups.

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Background: Laparoscopic splenectomy (LS) is becoming the "gold standard" technique for splenectomy. The aim of this study was to evaluate the hospital experience, body image, and cosmesis after LS or open splenectomy (OS).

Methods: Patients who underwent LS or OS were invited to fill out questionnaires evaluating their hospital experience, body image, and cosmetic results.

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Introduction: Minimally invasive techniques, such as laparoscopic appendectomy (LA), are thought to produce better cosmetic results. The aim of this study was to evaluate the body image and cosmesis of patients after both LA and open appendectomy (OA).

Patients And Methods: Between August 2007 and June 2008, patients who underwent LA or OA with the diagnosis of acute appendicitis were invited to participate in the study by filling out the body image questionnaire.

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A very important step in laparoscopic appendectomy is dissection of the appendiceal mesenteric pedicle. The aim of this study was to investigate the effect of LigaSure in laparoscopic appendectomy. Between August 2007 and June 2008, a total of 32 patients were included in the study.

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Introduction: Evaluation of pre- and postoperative serum CEA levels together has seldom been assessed for the prognosis of colorectal cancer (CRC).

Objective: To concurrently evaluate pre- and postoperative CEA as factors of relapse and survival.

Methods: The study consisted of 114 patients who had undergone surgery from February 2002 to June 2006 for CRC.

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Unlabelled: INTRODUCTION-AIM: The easiest method in postoperative analgesia is the infiltration of the wound with local anesthetic drugs. Although many local anesthetic drugs have been used for this type of infiltration, studies on levobupivacaine are rare. The aim of this study was to investigate the effects of different concentrations of levobupivacaine infiltration on wound healing.

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The aim of this study is to investigate the healing effect of hyperbaric oxygen (HBO) on colonic anastomoses in the presence of experimentally induced peritonitis. Thirty-two rats were allocated randomly into short-term anastomosis (STA), short-term anastomosis + HBO treatment (STA+HBO), long-term anastomosis (LTA), and long-term anastomosis + HBO (LTA+HBO) treatment groups. The STA and LTA groups were administered fluid resuscitation and antibiotics for 3 and 7 days, respectively, whereas the HBO treatment groups received additional HBO therapy for 3 and 7 days, respectively.

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A variety of negative opinions about repeated usage of relatively expensive resterilized synthetic meshes have been considered. It had been stated that resterilized polypropylene meshes inhibits fibroblastic activity, decreases proliferative activity, and increases apoptosis in human fibroblast culture, in vitro. The purpose of this study is the in vivo evaluation of the resterilized mesh repairs of abdominal hernia defects in rat models of incisional hernia by comparing primer repair and original mesh repairs.

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Background: Echinococcosis is still a serious problem particularly in endemic areas such as South and Central America, Mediterranean countries, and Russia. Furthermore, hydatid cysts of the lung are often indistinguishable from a variety of other pulmonary lesions such as lung tumors

Case Presentation: We herein present a 56 year old woman with breast cancer who presented with bilateral pulmonary nodules due to echinococcosis granulosis that mimicked metastatic breast cancer to the lung.

Conclusion: During the evaluation of the malignancies which could metastasize to the lung, it must be kept in mind that the appearance of bilateral multiple pulmonary masses can also be the sign of a pulmonary echinococcosis especially in endemic areas.

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