Epidemiological trends of HSV-1 and HSV-2 Central Nervous System Infections: A Retrospective Analysis from 2018 to 2023 from Saudi Arabia.

Herpes Simplex Virus (HSV) types 1 and 2 are significant etiologies to central nervous system (CNS) infections, leading to potential severe neurological consequences. Despite their global impact, our region's data on the epidemiology of HSV CNS infections remains limited. This study assessed the epidemiology and diagnostic trends of HSV-1 and HSV-2 CNS infections in a tertiary hospital in Southwestern Saudi Arabia from 2018 to 2023.

The impact of social media use on tolerance, community peace, online ethical awareness among adolescents in the United Arab Emirates.

Social media use has increased after the COVID-19, indicating several effects on users. Talking specifically about its effects on adolescents, several studies have witnessed its positive and negative consequences on young users. This research also aims to examine the positive effects of social media use on adolescents from a Media Mindfulness Perspective, including tolerance, community peace, and online ethical awareness.

Awareness of environmental risk factors contributing to asthma exacerbations among asthmatic patients in the Jazan region, Saudi Arabia.

Bronchial asthma is a common chronic airway disease marked by reversible obstruction and bronchial hyperresponsiveness. Effective management relies on patient understanding of the condition and available treatments. This study aimed to assess awareness of asthma risk factors, exacerbations, and disease severity among the population in the Jazan region of Saudi Arabia.

Mitral Valve Repair: Optimal Annual Case Volume for Surgery.

Background: Despite strong recommendations from multiple societies to pursue durable mitral valve repair (MVr), repair rates and outcomes remain inconsistent across the world. This is partly due to limited surgeon and center experience and lack of centralization of care for this technically challenging operation.

Objectives: The authors evaluate the association between annual case volume and contemporary long-term outcomes of patients undergoing isolated MVr.

Evaluation of hypertension knowledge and its association with medication adherence among hypertensive patients attending primary health centers: a cross-sectional study from eastern Saudi Arabia.

Background And Aim: The global healthcare system acknowledged the crucial role of disease knowledge in health outcomes and improving quality of life among patients with chronic disease. A lack of adequate knowledge and understanding of hypertension, its symptoms, and available treatments can lead to poor treatment outcomes. The present study aimed to determine the level of hypertension knowledge and associated factors among hypertensive patients.

Assessment of health behaviors of primary school teachers based on their nutritional knowledge and physical activity: A cross-sectional study in the Asir Region.

Background: Primary school teachers play a critical role as educators in imparting healthy eating behaviour and the importance of physical activity to prevent health issues. However, the teachers' health behaviors have not been studied much, particularly in Saudi Arabia. Understanding these factors is essential to developing interventions that enhance teachers' well-being and their ability to influence students positively.

Retrospective Analysis of Antibiotic Resistance Patterns of Uropathogenic With Focus on Extended-Spectrum -Lactamase at a Tertiary Central Hospital in Saudi Arabia.

Background And Aims: Urinary tract infections (UTIs) are a prevalent bacterial infection that has substantial implications for healthcare on a global scale. () is a gram-negative rod responsible for most UTI cases. ESBL-producing is widely recognized as a significant contributor to antibiotic resistance.

Corneal Epithelial Thickness Mapping in Healthy Population Corneas Using MS-39 Anterior Segment Optical Coherence Tomography.

Purpose: The corneal epithelium is the outermost layer of the cornea. It plays a vital role in both normal and pathological conditions of the eye surface and serves as a protective layer. This study aimed to evaluate corneal epithelial thickness (ET) and create a normative database of corneal ET for pediatric and adult age groups using MS-39 AS-OCT.

Electronic cigarette use among adolescents in Saudi Arabia: A national study, 2022.

Introduction: Electronic cigarette (e-cigarette) use has increased globally among adolescents. However, data on its use among adolescents in Saudi Arabia remain limited. Therefore, this study describes the characteristics and factors associated with e-cigarette use in this population.

Association between cognitive restraint, emotional eating, uncontrolled eating, and body mass index among health care professionals.

Among healthcare professionals (HCPs), the demanding nature of their work, irregular schedules, and high-stress environments can significantly influence their eating behaviors. This study's objectives were to assess the relationship between cognitive restraint (CR), emotional eating (EE), uncontrolled eating (UE), and body mass index (BMI) and identify the sociodemographic factors associated with CR, EE, and UE among HCPs. A cross-sectional study and a simple random sampling technique were employed.

Functional neurological disorder treated with psychoeducation: A case report.

Rationale: Psychogenic tremor (PT) is the most common subtype of psychogenic movement disorder, characterized by involuntary movement, and is usually related to occupational injuries or accidents. Psychogenic movement disorder falls under the category of functional neurological disorders, which are diagnosed based on the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders.

Patient Concerns: A 25-year-old Saudi male with a history of recurrent superior ventricular tachycardia presented to the emergency department with tremors affecting all his extremities for 8 days.

Effectiveness of ChatGPT in facilitating learning for students with special educational needs: An empirical study in Saudi Arabia.

Study Purpose: This paper aims to explore the effectiveness of ChatGPT in facilitating learning for medical students with special educational needs (SEN) while acknowledging and addressing the challenges that SEN students may encounter in utilizing this technology.

Methods: This cross-sectional survey study assessed ChatGPT's efficacy in supporting medical students with SEN across three Saudi Arabian universities. Utilizing purposive and convenience sampling, a questionnaire was administered to 283 SEN students.

Trends and gaps in hydroxychloroquine and COVID-19 research (2020-2023): Performance and conceptual mapping.

Background: Hydroxychloroquine and Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs with well-known anti-inflammatory and antiviral effects used to treat various diseases, with few side effects. After COVID-19 emergence, numerous researches from around the world have examined the potential of using CQ or HCQ as potential treatment of COVID-19. However, conflicting outcomes have been found in COVID-19 clinical trials after treatment with CQ or HCQ.

Protective Effect of Vitamin D Supplementation Against Atherosclerotic Cardiovascular Disease in Type 1 Diabetes Mellitus Model.

Introduction: Cardiovascular disease (CVD) is a leading cause of mortality on a global scale, with a higher prevalence observed among men. This study investigated the protective effect of vitamin D supplementation on CVD.

Methods: A cohort of thirty mice was divided into three groups: control, T1 diabetic, and T1 diabetic groups that received vitamin D treatment.

Prophylactic administration of PEPITEM in experimental autoimmune encephalomyelitis delays disease onset, inhibits leukocyte infiltration, and alleviates severity.

Background: Multiple sclerosis (MS) is a chronic, immune-mediated neurological disorder in which the immune system mistakenly attacks the myelin sheath, affecting the communication between the brain and the rest of the body.

Objective: This study investigated the prophylactic use of peptide inhibitor of trans-endothelial migration (PEPITEM), a novel peptide, in alleviating experimental autoimmune encephalomyelitis (EAE), a mouse model for Multiple Sclerosis (MS).

Methods: Female C57BL/6 female mice were assigned to the control, untreated EAE, or PEPITEM group.

Prevalence and control of hypertension in COVID-19 positive cases.

Background: The coronavirus disease (COVID-19) is an infectious disease caused by the newly discovered SARS-CoV-2 virus. Patients diagnosed with COVID-19 experience several complications including hypertension or elevated blood pressure which is a serious medical condition that significantly increases the risks of heart, brain, and kidney diseases.

Objectives: To assess the prevalence and control of hypertension in COVID-19 patients.

Basidiobolomycosis: Unusual Cause of Colonic Perforation.

Basidiobolomycosis is a rare fungal infection that is triggered by the environmental saprophyte . Basidiobolomycosis usually presents as an infection beneath the skin and seldom impacts the digestive system. There is no clear clinical presentation, and the majority of initial cases are misdiagnosed.

Prevalence of piriformis syndrome and its associated risk factors among university students in Pakistan: a cross-sectional study.

Objective: To determine the prevalence of piriformis syndrome (PS) among undergraduate university health sciences students aged 18 to 25 and assess the significant predictors of PS regardless of its type and severe PS in particular.

Design: A cross-sectional study.

Setting: The study was conducted at a tertiary care hospital of a public university in Pakistan from December 2023 to May 2024.

Acephate Exposure Induces Transgenerational Ovarian Developmental Toxicity by Altering the Expression of Follicular Growth Markers in Female Rats.

Acephate is an organophosphate foliar and soil insecticide that is used worldwide. In this study, the transgenerational ovarian developmental toxicity caused by acephate, along with its in utero reprogramming mechanisms, were explored. Thirty female virgin Wistar albino rats were randomly assigned to three groups: one control group and two acephate treatment groups.

Community awareness regarding smokeless tobacco (Shamma) as a cause of oral cancer in Jazan region, Saudi Arabia: A cross-sectional study.

Introduction: Oral cancer has emerged as a significant public health issue, with 90% of instances because of avoidable causes. Smokeless tobacco usage is thought to be a substantial source of cytological alterations in the oral mucosa, and snuff (Shamma) is often used in Saudi Arabia. In this study, we investigated community awareness of Shamma as a cause of oral cancer in the Jazan region's general population.

Factors associated with tobacco use among Saudi Arabian youth: Application of the Theory of Planned Behavior.

Introduction: The epidemic of tobacco use poses one of the most severe public health challenges globally, responsible for over 8 million deaths annually according to the World Health Organization (WHO). This study investigates the factors associated with tobacco use among Saudi Arabian youth using the Theory of Planned Behavior (TPB) framework.

Methods: A cross-sectional study used the 2022 Global Youth Tobacco Survey (GYTS) to assess tobacco use among 5610 Saudi students aged 13-15 years.

Knowledge, Attitudes, and Practices of Adult Residents of Riyadh Regarding Sunstrokes.

Objectives This study aims to evaluate the knowledge, attitudes, and practices of adult residents in the city of Riyadh regarding sunstrokes and identify the preferred channel for spreading awareness about sunstrokes among this population. Methods This study employed an analytical cross-sectional design targeting Riyadh city residents aged 18 and older. A multistage random sampling technique was used, resulting in a sample size of 681 participants.

The Association Between Antioxidant Enzyme Polymorphisms with Type 2 Diabetes Mellitus in Jazan Province.

Introduction: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which results in initiates oxidative stress and disrupts various cellular pathways. In this study, we examined the relationship between polymorphisms in antioxidant enzymes, specifically glutathione peroxidase 1 (GPx1) and catalase (CAT), and the susceptibility to T2DM in a Saudi population from the Jazan Province.

Methods: A total of 419 participants were evaluated, including 247 T2DM patients and 172 controls.

Factors influencing engagement in oral cancer prevention activities among dental students and professionals in Saudi Arabia.

Background: Oral cancer is a pressing health concern in the Saudi Arabia (SA), with rising incidence and mortality rates. Despite the efforts in raising awareness, gaps persist in knowledge, attitudes, and practices (KAP) related to oral cancer prevention (OCP) among dental health professionals. This study aimed to identify the key factors influencing engagement in oral cancer prevention activities among dental students and professionals in Saudi.