Publications by authors named "Alharbi N"

Objectives: Hearing impairment during childhood is a widespread health issue. Prompt recognition and timely intervention are vital for the advancement of language skills. Insufficient parental knowledge can lead to a delay in diagnosing and treating a condition, which can have a negative impact on academic performance.

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Nanoparticle technology has revolutionized breast cancer treatment by offering innovative solutions addressing the gaps in traditional treatment methods. This paper aimed to comprehensively explore the historical journey and advancements of nanoparticles in breast cancer treatment, highlighting their transformative impact on modern medicine. The discussion traces the evolution of nanoparticle-based therapies from their early conceptualization to their current applications and future potential.

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This work develops Fe-Ni particles loaded on biochar (Fe-Ni/BC) to remove U(VI) efficiently. Fe-Ni bimetallic particles loaded on biochar (BC) can improve stability and reactivity, and the mesoporous structure of BC can effectively reduce Fe aggregation. The removal ability of Fe-Ni/BC is higher than that of Fe-Ni, BC, and Fe/BC.

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Eruptive pseudoangiomatosis (EP) is a rare cutaneous condition that usually resolves spontaneously within a few days and is more frequently seen in the pediatric age group. It is characterized by the sudden onset of asymptomatic small erythematous hemangioma-like papules encircled by a pale halo. The precise pathogenesis is unknown; however, multiple environmental triggers have been reported.

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Background And Aim: Vitamin B12 deficiency is a recognized concern among patients with type 2 diabetes mellitus (T2DM) using metformin due to its potential impact on health outcomes. This study investigates the prevalence of vitamin B12 deficiency among diabetic patients using metformin at Dr. Sulaiman Al Habib Medical Group (HMG) hospitals.

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The emergence of various diseases such as cardiovascular, aging and cancer are due to oxidative stress as well as the shortage of enough antioxidant materials. Our study was intended to analyze the anticancer, antimicrobial, wound healing as well as hepatoprotective activities of purified sulfated polysaccharides derived from The sulfated polysaccharide was subjected to partial purification using DEAE cellulose. The sulfated fraction was identified by HPLC, FTIR, H-NMR and GC-MS.

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Article Synopsis
  • Lipid nanoparticles (LNPs) are effective carriers for delivering mRNA-based therapies and other drugs, improving targeted delivery to specific cells or tissues.
  • LNPs come in various types, such as liposomes and lipid-polymer hybrids, and their preparation involves altering their structural and physical properties using different methods.
  • The review highlights potential biological sources for lipids, like those from plants and microorganisms, and suggests eco-friendly sources for future LNP production.
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Article Synopsis
  • * A case study is presented about a 51-year-old woman with a Grade 2 meningioma that ultimately transformed into a Grade 1 meningioma after surgical intervention and follow-up.
  • * The transformation from Grade 2 to Grade 1 meningioma is rarely documented and not well-understood, leading to insights on its natural progression and the importance of radiological and histopathological assessments in treatment planning.
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Objectives: The growing trend of minimally invasive approaches has encouraged the application of partial coverage designs in restorative dentistry. This study aimed to evaluate the cyclic fatigue performance of different CAD-CAM materials used in various partial coverage designs for premolar restorations.

Methods: A freshly extracted upper premolar was prepared using a high-speed handpiece to create mesio-occluso-distal (MOD) cavities with standardized dimensions.

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In this report, we discuss a rare case of pleomorphic adenoma in the accessory parotid gland of a 39-year- old male, which is generally a difficult tumor to manage because of the danger of facial scarring and nerve injury from external incisions. A minimally invasive trans-oral surgical technique was used, resulting in a successful resection without the usual complications, demonstrating a promising option that focuses on cosmetic and functional benefits. The importance of complete preoperative evaluations is emphasized, as is the possibility for broader applicability with additional study, establishing the technique's efficacy to improve outcomes for patients in similar circumstances.

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Background: Preconception care (PCC) aims to address health risks before conception for better pregnancy outcomes. Effective PCC starts before pregnancy and involves interventions to improve well-being and prevent adverse outcomes. Unintended pregnancies and pre-existing illnesses increase risks.

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Background: Stroke is a significant contributor to both mortality and compromised physical function. Endovascular thrombectomy (EVT) is now the recognized standard of care for anterior circulation acute ischemic stroke (AIS) with large vessel occlusion (LVO), especially when favorable brain images are evident within 24 h of symptom onset. This study elucidated the characteristics, clinical profiles, and outcomes of patients who underwent EVT for AIS.

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Background: The recent unprecedented foodborne botulism outbreak in Saudi Arabia necessitated an assessment of healthcare workers' (HCWs) knowledge, attitudes, and practices (KAP). This study assessed healthcare workers' knowledge regarding the transmission, contagiousness, presentation, and diagnosis of foodborne botulism, as well as their management practices, including contacting public health authorities, administering antitoxin, preparedness to respond to botulism cases and consulting generative Artificial Intelligent (AI)-chatbots, like ChatGPT.

Methods: A cross-sectional online survey targeting Saudi HCWs was conducted from May 6-19, 2024, following the first foodborne botulism outbreak.

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Neuroendocrine tumors (NETs) are usually found in the gastrointestinal tract and pancreas; however, they are rare in the middle ear. The presentation of vague symptoms, such as tinnitus and conductive hearing loss, complicates the diagnosis. We present a 46-year-old male with a history of right ear discharge and a previous canal wall-down mastoidectomy, suspected to have cholesteatoma recurrence.

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Article Synopsis
  • AI is changing pediatric dentistry by improving diagnostics, treatment planning, and behavior management in children.
  • Current applications include detecting dental anomalies, categorizing fissure sealants, assessing age, and managing patient behavior.
  • The review highlights emerging trends in AI that could revolutionize the field and aims to inform professionals about the benefits of AI in overcoming traditional challenges and enhancing children's oral health.
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Article Synopsis
  • - The study investigates potential health risks associated with mobile phone use, focusing on how radiofrequency electromagnetic (RF-EM) exposure might affect heart function, specifically looking at electrocardiograms (ECGs) and heart rate variability (HRV) due to changes in blood pressure and body mass index (BMI).
  • - Researchers analyzed data from 20 healthy males and used a sophisticated multivariate approach, including the one-sample Hotelling test, to assess differences in key cardiac variables (P-R, QRS, QT, ST, and HR) after exposure to mobile phone EMFs at various body locations.
  • - Findings indicated significant changes in ECG intervals and heart rate after initial EMF exposure, regardless of participant BMI, suggesting
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Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) are a novel class of medications promising for treating type 2 diabetes mellitus (T2DM) and obesity-related conditions such as cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD). This comprehensive literature review examines available research on these medications, focusing on their mechanisms of action, clinical effectiveness, safety profiles, and socioeconomic implications. A comprehensive search was performed using the PubMed, EMBASE, and Cochrane Library databases.

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Aim and background Medical emergencies (MEs) pose urgent threats to life and occur frequently, with primary care providers seeing at least one emergency per year. Common MEs include asthma, anaphylaxis, seizures, and cardiac arrest. However, many medical offices are ill-equipped to handle these emergencies.

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Objective: The objective of this study was to describe medical students' learning styles and locus of control (LOC) and to determine their association with academic achievement.

Methods: A cross-sectional study was performed at a health science university in Saudi Arabia. A sample of 158 medical students completed Kolb's learning style and locus of control scales.

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Introduction: Artificial intelligence (AI) is commonly used in the modern day medical system for medical and dental imaging diagnostics, decision support, precision, hospital monitoring, robotic assistants, and so on. All branches of dentistry have a role of AI, like endodontics, cancer diagnosis, and cephalometric analysis. With the advancing technology, dental professionals need to upgrade themselves.

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Wilms tumor (WT) is the most common form of pediatric renal tumor, accounting for over 90% of cases followed by hypernephroma. Some pediatric patients with WT (10%) experience relapse or metastasis and have poor survival rates. PD-L1 assists cancer cells in escaping damage from the immune system.

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Peripheral nerve sheath tumors (PNSTs), while uncommon, can have a significant impact on appearance and quality of life, especially when they form in prominent areas such as the nose dorsum. We discuss a case of a 29-year-old woman who developed a benign PNST on the right side of her nasal ala. This tumor gradually grew, impairing her face appearance.

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Background: Globally, approximately 70 million people suffer from epilepsy. Infants constitute a significant percentage of these cases. Hence, there is a significant need for better understanding of the pathophysiology of epilepsy through laboratory and radiological methods for early detection and optimized management.

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