Publications by authors named "Alguacil J"

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  • The study investigated pollution signatures in marsh sediments of the Odiel-Tinto Estuary to guide restoration efforts, focusing on various pollution sources like acid mine drainage and agricultural runoff.
  • We analyzed chemical elements and sediment characteristics across multiple marshes, creating spatial maps to visualize pollution distributions from different sources.
  • Our findings can help identify responsible polluters, assess the most affected areas, and serve as a baseline for evaluating the future impacts of the RESTORE 2030 restoration plan.
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Background: 10% of postmenopausal breast cancer cases are attributed to a high body mass index (BMI). BMI underestimates body fat, particularly in older women, and therefore the cancer burden attributable to obesity may be even higher. However, this is not clear.

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  • * It analyzed data from 805 CRC survivors using the SF-12 and FCSI questionnaires, revealing that factors like age, sex, and geographic area significantly impact both physical and mental quality of life.
  • * The findings suggest that older women have the worst HRQoL scores, indicating a need to identify these factors to create strategies that improve survivorship outcomes and reduce the negative impacts of cancer.
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The development of nuclear fusion as a safe and virtually limitless power source is receiving growing attention in the context of looming energy crisis and climate change. ITER project stands as the flagship international initiative and is advancing steadily. The construction of the Tokamak Complex is nearly finished, and the assembly of core components has begun on site.

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Potential differential and non-differential recall error in mobile phone use (MPU) in the multinational MOBI-Kids case-control study were evaluated. We compared self-reported MPU with network operator billing record data up to 3 months, 1 year, and 2 years before the interview date from 702 subjects aged between 10 and 24 years in eight countries. Spearman rank correlations, Kappa coefficients and geometric mean ratios (GMRs) were used.

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  • The study investigates the impact of cigarette smoking on breast cancer risk, highlighting the conflicting effects it may have due to its carcinogenic and antiestrogenic properties.
  • Analysis from a large population-based study involving 1733 breast cancer cases and 1903 controls revealed that smoking increases the risk of premenopausal breast cancer, especially in long-term smokers (≥30 years).
  • Conversely, for postmenopausal women, smoking may lower the risk of breast cancer, particularly in those who have stopped smoking for at least 10 years, indicating that menopausal status significantly influences the relationship between smoking and breast cancer risk.
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Background: Very little information is available on the population distribution and on sociodemographic predictors of body concentrations of rare earth elements (REE) and other chemicals used in the manufacturing of high-tech devices.

Objectives: To analyze the distribution and associated sociodemographic factors of blood concentrations of chemical elements (including some metals, essential trace elements, rare earth elements and other minority elements) in a representative sample of the general population of Barcelona (Spain).

Methods: A sample of participants in the Barcelona Health Survey of 2016 (N = 240) were interviewed face-to-face, gave blood, and underwent a physical exam.

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  • Endometrial cancer is the most common gynecological cancer in developed countries, and its incidence is expected to rise, prompting the need to identify modifiable risk factors for prevention.
  • This study investigates the link between occupational pesticide exposure and endometrial cancer using data from 174 cancer cases and 216 control subjects in Spain, utilizing structured questionnaires and a job-exposure matrix to assess pesticide exposure.
  • The findings indicate a significant association between pesticide exposure and endometrial cancer, particularly for insecticides, fungicides, and herbicides, with the strongest links found in agricultural activities, suggesting a need for further exploration of pesticides’ role in cancer development.
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  • The World Health Organization estimates that 20% of university students have faced major depressive disorder, and factors like low omega-3 fatty acids and vitamin D, found in fish, may play a role in depression.
  • A study surveyed 11,485 Spanish university students to assess the prevalence of depression and fish consumption habits, finding a 10.5% depression rate, particularly among women, older students, and those living away from home.
  • The research indicated that 67% of students met fish intake recommendations, with 44.2% consuming fish 1-2 times per week; low fish consumption was linked to an increased risk of depression, but individual circumstances were the most significant factors influencing disorder development.
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Background: Acidic urine pH is associated with rapid hydrolysis of N-glucuronide conjugates of aromatic amines into metabolites that may undergo metabolism in the bladder lumen to form mutagenic DNA adducts. We previously reported that consistently acidic urine was associated with increased bladder cancer risk in a hospital-based case-control study in Spain. Here, we conducted a separate study in northern New England to replicate these findings.

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Objective: To describe the frequency and typology of the presenting symptom of women diagnosed of breast cancer in Spain and their socio-demographic profile.

Methods: Descriptive study nested in a population epidemiological study (MCC-SPAIN) in 10 Spanish provinces. Between 2008 and 2012, 836 histologically confirmed incident cases of breast cancer were recruited who reported some symptom prior to diagnosis in a direct computerized interview.

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Objective: Heat exposure and heat stress/strain is a concern for many workers. There is increasing interest in potential chronic health effects of occupational heat exposure, including cancer risk. We examined potential associations of occupational heat exposure and colorectal cancer (CRC) risk in a large Spanish multi-case--control study.

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  • Breast and prostate cancers have been linked to circadian disruption, but previous research on sleep duration's impact on cancer risk has shown inconsistent results.
  • This study, part of the MCC-Spain project, analyzed a large population of breast (1738 cases) and prostate cancer (1112 cases) patients alongside matched controls, focusing on various sleep characteristics like duration, quality, and napping habits.
  • The findings indicated no strong associations between sleep patterns and cancer risk, but a notable positive relationship was found between breast cancer risk and taking habitual siestas, especially when frequency or duration increased, alongside correlations between recent sleep problems and both cancer types.
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Background: The association of meat intake with gastric adenocarcinoma is controversial. We examined the relation between white, red, and processed meat intake and gastric adenocarcinoma, considering doneness preference and cooking methods, by histological subtype and anatomical subsite.

Methods: MCC-Spain is a multicase-control study that included 286 incident gastric adenocarcinoma cases and 2993 controls who answered a food-frequency questionnaire.

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Background: Heat exposures occur in many occupations. Heat has been linked to key carcinogenic processes, however, evidence for associations with cancer risk is sparse. We examined potential associations between occupational heat exposure and prostate cancer risk in a multi-country study.

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Objective: To extend knowledge about the long-term use of hormones in hormone therapy or oral contraception as prognostic factors in breast cancer.

Methods: The MCC-Spain project is a cohort of 1,685 women with incident breast cancer recruited in Spain. Recruitment was carried out between 2007 and 2010, and the follow-up finished in December 2017.

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Despite the increasing trend in the incidence of breast cancer in recent decades, mortality has decreased in developed countries. The general objective of the study is to analyse the functioning and organisation of the care process for breast cancer treatment in Andalusia (Spain) in order to identify possible barriers and facilitators that may be affecting its effectiveness and, therefore, the survival of the disease. A qualitative method was adopted based on 19 semi-structured interviews with health professionals from different specialities in two Andalusian provinces: Huelva (mortality rate higher than the national average) and Granada (mortality rate similar to the national average).

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Background: Toenails are commonly used as biomarkers of exposure to zinc (Zn), but there is scarce information about their relationship with sources of exposure to Zn.

Objectives: To investigate the main determinants of toenail Zn, including selected sources of environmental exposure to Zn and individual genetic variability in Zn metabolism.

Methods: We determined toenail Zn by inductively coupled plasma mass spectrometry in 3,448 general population controls from the MultiCase-Control study MCC-Spain.

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Among university students there has been evidence that the COVID-19 pandemic increased their psychological distress, exacerbated by social restrictions. The main objective of this study was to explore the impact of the COVID-19 pandemic on the prevalence and patterns of cannabis use among university students, in contrast to previous trends since 2012. Data from 10,522 first-year university students (73.

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Circadian nutritional behaviors, defined by the daily eating/fasting cycle, have been linked with breast cancer. This study aimed to further disentangle the association of nighttime fasting duration and time of breakfast with breast cancer risk. We analyzed data from 1,181 breast cancer cases and 1,326 population controls from the Spanish multicase-control study (MCC-Spain), 2008-2013.

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We explored the association between residence in an area polluted with metals and neurobehavioral performance in children aged 9 to 11. A cross-sectional study was conducted with thirty boys and thirty girls aged 9 to 11 from public schools in a heavily industrialized area, matched by age (±4 months) and gender with 15 boys and 15 girls from public schools in cities without relevant industrial activity. Neurobehavioral performance was assessed with the Behavioral Assessment and Research System.

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