Publications by authors named "Alfredo Perales-Puchalt"
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Synopsis of recent research by authors named "Alfredo Perales-Puchalt"
- Alfredo Perales-Puchalt's recent research focuses on innovative cancer immunotherapies, including personalized neoantigen vaccines, bispecific antibodies, and targeting unique antigens associated with specific cancers like hepatocellular carcinoma, multiple myeloma, and ovarian cancer.
- Key findings from his studies indicate that personalized therapeutic cancer vaccines can enhance the efficacy of PD-1 inhibitors, and that BCMA-targeting bispecific antibodies significantly impact humoral immunity, which can lead to higher infection rates in treated patients.
- Perales-Puchalt has also demonstrated the potential of targeting specific tumor antigens and immune checkpoints, such as Siglec-7 and BTN3A1, to improve anti-tumor responses in various malignancies, highlighting the significance of incorporating immune engagement strategies into cancer treatment.