Clinical variability of children with anti-N-methyl-D-aspartate receptor encephalitis in southern Brazil: a cases series and review of the literature.

Purpose: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an immune-mediated disease of the central nervous system (CNS). The aim of this study was to describe the variability of clinical presentation in anti-NMDAR encephalitis, treatment and outcomes in a case series of children and adolescents.

Methods: Retrospectively analyse patients diagnosed with anti-NMDAR encephalitis, from 2010 to 2018.

[Management of head injury in children].

OBJECTIVE: To make pediatricians aware of ideas about how to handle head injury in children under and over 2 years of age, to facilitate understanding and to allow a rethinking about the necessary care when attending children with head injury. SOURCES: A bibliographic review of the theme based on Medline. SUMMARY OF THE FINDINGS: The following aspects were analyzed: the overall epidemiological aspects, the concept and the physiopathology of the damage caused by brain trauma.

[Acute coma in children: etiology, morbidity and mortality].

Objective: An analysis was conducted on the etiology and the morbi-mortality of pediatric patients in acute coma, hospitalized at the Intensive Care Unit of Hospital Infantil Pequeno Príncipe (UTI-HIPP).

Method: One hundred and four control sheets of children hospitalized at the UTI-HIPP and diagnosed as being in acute coma were analyzed. The Glasgow coma scale duly modified for children was used, with a score count equal to or lower than 8 points.