Publications by authors named "Alfredo J Rodrigues-Neto"

Purpose: Historically, somatropin has been used for conditions related with ageing, but since the marketing of recombinant human growth hormone (rhGH), increasing promotional pressure has prompted aesthetic uses, despite lack of evidences about its efficacy and safety for those purposes.

Methods: A routine analysis of the Pharmacovigilance Center of São Paulo (Brazil) showed reports of suspected adverse reactions in young adults and mature patients receiving rhGH. After presuming an off-label use of this expensive product, a drug utilisation study within the pharmacovigilance database has been carried out.

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Synopsis of recent research by authors named "Alfredo J Rodrigues-Neto"

  • - Alfredo J Rodrigues-Neto's research primarily focuses on pharmacovigilance, particularly identifying and addressing medicine misuse in specific demographics, as demonstrated in his study on recombinant human growth hormone (rhGH) used for aesthetic purposes.
  • - His analysis revealed a concerning trend of off-label use of rhGH, prompting an evaluation of adverse reactions reported among young adults and mature patients, highlighting the importance of monitoring drug safety in these groups.
  • - Additionally, Rodrigues-Neto has critically reviewed existing guidelines, such as the Beers Criteria for elderly adults, to identify potential gaps in medication safety assessments, reflecting his commitment to improving drug safety protocols for vulnerable populations.