Publications by authors named "Alfredo Geovanny Pech-Aguilar"
Background: Gastric cancer (GC) is one of the most frequent cancer types in Mexico. The primary method used as a treatment is surgical resection. The role of surgery in increasing survival is controversial.
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- * The lipid accumulation product (LAP) is used to evaluate central fat and serves as a marker for cardiovascular and metabolic risks, and this study explores its link to oxidative stress biomarkers.
- * In a study of 250 adults, a significant positive relationship was found between LAP and oxidative stress (measured by MDA levels), particularly in women, suggesting that higher LAP levels might indicate increased oxidative stress.
Background: Activation of the immune system response is associated with the generation of oxidative stress (OS). Several alterations are involved in OS, such as excessive production of reactive oxygen species (ROS) and decreased antioxidant activity, which together lead to an imbalance in redox status. The role of OS during SARS-CoV-2 infection is not fully understood.
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- * Traditional Mexican medicine utilizes various plants with bioactive compounds like polyphenols and flavonoids to help treat or prevent UL.
- * The beneficial effects of these plants may involve activities that prevent stone formation, supported by antioxidant, anti-inflammatory, and antimicrobial properties.
[Updated review on the pathophysiology of Chagas cardiomyopathy].
Rev Med Inst Mex Seguro Soc
May 2020
More than 110 years after Chagas disease discovery, some aspects of the mechanisms involved in the physiopathology of heart damage are still unknown. Previously, Trypanosoma cruzi was considered to be the only cause of myocardial injury. Currently, there are other known mechanisms involved in the physiopathology of Chagas heart disease, including the immune-inflammatory response, autoimmunity, microvascular abnormalities and nerve damage, which are interrelated and contribute to cardiac damage.
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