Publications by authors named "Alfredo Dias Oliveira-Filho"
Background: Preeclampsia (PE) is a significant cause of maternal mortality worldwide, affecting 2% to 8% of pregnancies. The World Health Organization recommends the use of low-dose acetylsalicylic acid (100 mg of aspirin) and 1.5 to 2 g of calcium carbonate during pregnancy to prevent PE.
View Article and Find Full Text PDFOne of the measures for monitoring microbial resistance is the calculation of the defined daily dose of antimicrobial agents. For this calculation, the weight of an adult of 70 kg is used as a standard, so that application in neonatology is not possible. The aim of this study is to describe the use profile and calculate the defined daily dose (DDD) of antimicrobials in a neonatal intensive care unit (NICU) of a public hospital in the interior of Bahia, Brazil.
View Article and Find Full Text PDFTranslation, transcultural adaptation, and validation of the Brazilian Portuguese version of the general medication adherence scale (GMAS) in patients with high blood pressure.
Explor Res Clin Soc Pharm
December 2024
Objective: To validate the General Medication Adherence Scale (GMAS) in Brazilian Portuguese for hypertensive patients.
Methods: The GMAS-English was translated into Brazilian Portuguese and adapted for cultural appropriateness by a translation process and expert panel. A cross-sectional study was conducted in northeast Brazilian cardiology divisions of public and private hospitals, interviewing hypertensive patients.
Background: High-alert medication (HAM) is more predictable to cause significant harm to the patient, even when used as intended. The damage related to the HAM lead not only suffering to the patient, but also raise the additional costs associated with care.
Objective: Evaluate the incidence of drug-related adverse events related to the use of high-alert medications.
Article Synopsis
- Around 5-7% of pregnant women experience hypertension and may require medication, but there hasn't been enough research on how drug-related issues affect their health after childbirth, especially for those with a history of preeclampsia.
- This study examined 600 postpartum women diagnosed with preeclampsia in Brazil to see how drug-related problems (such as missed medications or lack of prescriptions) impacted their hospital stay and recovery.
- Results showed that women with drug-related problems had a longer average hospital stay (5.4 days) compared to those without such issues (4.4 days), indicating that these problems can hinder recovery after labor.
Article Synopsis
- The study aimed to identify how common harm from high-alert medications (HAM) is after medication errors in hospitals, finding varied prevalence rates from 3.8% to 100%, with an average of 16.3%.
- Research revealed that only 0.01% of these medication errors led to patient death, while the severity of errors varied significantly among studies.
- Most harm was linked to errors involving potassium chloride, insulin, and epoprostenol, while anticoagulants showed the least harm; the analysis was complicated by differing methodologies in the studies reviewed.
Background: Because pregnant women are often excluded from clinical trials, there is still very limited information about the risk and safety of prescription drugs during pregnancy.
Objective: We aimed to determine the prevalence of Adverse Drug Reactions (ADRs) in high-risk pregnant women after hospital admission. A prospective study was carried out in a teaching maternity hospital in Brazil during six months.
Medications are perceived as health risk factors, because they might cause damage if used improperly. In this context, an adequate assessment of medication use history should be encouraged, especially in transitions of care to avoid unintended medication discrepancies (UMDs). In a case-controlled study, we investigated potential risk factors for UMDs at hospital admission and found that 150 (42%) of the 358 patients evaluated had one or more UMDs.
View Article and Find Full Text PDFBackground: Atrioventricular reentrant tachycardias account for approximately one third of cases referred for electrophysiological study (EPS). The anatomical substrate responsible for the reentry is an accessory pathway (AP) able to conduct the electrical stimulus in an anterograde, retrograde or bidirectional manner.
Objective: To evaluate the correlation of AP location with the male and female genders and AP clinical presentation, whether manifest or concealed.
Introduction: Left ventricular hypertrophy (LVH) is an independent predictor of cardiovascular risk in patients with chronic renal disease (CRD) on hemodialysis (HD).
Objective: To show the usefulness of chest radiography in the diagnosis of LVH in CRD patients on HD.
Methods: Cross-sectional study including 100 patients (58 men and 42 women), mean age 46.
Background: The Morisky Medication Adherence Scale (MMAS-8) remains one of the most widely used mechanisms to assess patient adherence. Its translation and testing on languages in addition to English would be very useful in research and in practice.
Objective: To translate and examine the psychometric properties of the Portuguese version of the structured self-report eight-item Morisky Medication Adherence Scale among patients with hypertension.
Background: Non-adherence to treatment is an important and often unrecognized risk factor that contributes to reduced control of blood pressure (BP).
Objective: To determine the association between treatment adherence measured by a validated version in Portuguese of the 8-item Morisky Medication Adherence Scale (MMAS-8) and BP control in hypertensive outpatients.
Methods: A cross-sectional study was carried out with hypertensive patients older than 18 years, treated at six of the Family Health Strategy Units in Maceió (AL), through interviews and home blood pressure measurements, between January and April 2011.