Evolution of Zika prevalence in a dengue hyperendemic municipality in Southern Mexico after the outbreak of 2015 to 2017.

Objective: Estimate the Zika prevalence in a dengueendemic municipality in Mexico, after the outbreak of 2015 to 2017.

Materials And Methods: Three serosurveys were conducted in Tapachula, Chiapas, in September 2018, March 2019 and November 2019. A commercial ZIKV and DENV anti-NS1 IgG ELISA were used to estimate each prevalence, their performance and adjustment of the cut-off value were compared with an in-house DENVs and ZIKV anti-EDIII IgG ELISA and the microneutralization test.