Publications by authors named "Alfonso Arranz Martin"
Article Synopsis
- Malnutrition is a common issue in Cystic Fibrosis (CF) that negatively affects lung function, but new therapies like elexacaftor-tezacaftor-ivacaftor (ELX/TEZ/IVA) are improving patient care and outcomes.
- This study evaluated 36 patients with CF to see how ELX/TEZ/IVA affected their body composition (using Bioelectrical Impedance Analysis) and respiratory function (spirometry), taking measurements before and after six months of treatment.
- Results showed a significant increase in Body Mass Index (BMI), fat mass, and lung function (%FEV1), with correlations indicating that higher fat mass was associated with lower lung function, while better lung
Introduction: Alpelisib is an orally selective PI3K alpha inhibitor recently available for the treatment of advanced breast cancer. PI3K pathway is an intracellular signaling pathway that plays an important role in regulating glucose metabolism. Hyperglycemia is the most common adverse event associated.
View Article and Find Full Text PDFObjective: To report the clinical characteristics of patients with latent autoimmune diabetes in adults (LADA), and to ascertain their metabolic control and associated chronic complications.
Methods: Patients with DM attending specialized medical care in Madrid who met the following criteria: age at diagnosis of DM >30years, initial insulin independence for at least 6months and positive GAD antibodies were enrolled. Clinical profiles, data on LADA diagnosis, associated autoimmunity, C-peptide levels, therapeutic regimen, metabolic control, and presence of chronic complications were analyzed.
Objective: To analyze the available information about continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM) systems in the public health care system of the Community of Madrid.
Material And Methods: A survey consisting of 31 items was sent to the 28 endocrinology department of the Madrid public hospitals. Items focused on CSII and CGM and included patients' registrations, as well as data regarding healthcare, administrative, and logistic aspects.
We present our experience with low-dose cinacalcet to normalize serum calcium in patients with primary hyperparathyroidism (PHPT) not eligible for surgery. We analyzed the impact of this drug on various parameters of calcium-phosphorus metabolism and its tolerability profile. We recruited 17 patients diagnosed with PHPT who had hypercalcemia and also met one or more of the following inclusion criteria: elevated risk for parathyroidectomy, persistent/recurrent PHPT after previous parathyroid surgery or refusal to undergo surgery.
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