Publications by authors named "Alfons Jm Balm"
Introduction: This study aims to quantify surgical site complications (SSC) after isolated salvage neck dissection (ND) compared with primary ND.
Patients And Methods: Between 1997 and 2017 in the Netherlands Cancer Institute - Antoni van Leeuwenhoek, a total of 323 isolated NDs were performed in 308 patients: primary ND (n = 144), post-radiotherapy (RT) ND (n = 53) and post-chemoradiotherapy (CRT) ND (n = 126). Patient, tumor and therapy characteristics were recorded.
Article Synopsis
- There is a worry that a type of tumor in the salivary gland, called pleomorphic adenoma, can turn cancerous, which makes doctors want to treat it hard if it comes back.
- Scientists studied a specific case and found that changes in the DNA helped them see how the tumor changed from benign to cancerous.
- They identified particular DNA changes in the tumor that stayed the same even when it came back as cancer, showing that studying these changes can help doctors recognize when a tumor becomes malignant.
Nowadays, a substantial number of head and neck cancer patients are treated by organ-preserving chemoradiation (CRT), with a possible increased risk of complications after planned or salvage neck dissections. We try to determine the risk pattern of surgical site complications (SSC) post-CRT.
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