Recovery and resilience after a nuclear power plant disaster: a medical decision model for managing an effective, timely, and balanced response.

Resilience after a nuclear power plant or other radiation emergency requires response and recovery activities that are appropriately safe, timely, effective, and well organized. Timely informed decisions must be made, and the logic behind them communicated during the evolution of the incident before the final outcome is known. Based on our experiences in Tokyo responding to the Fukushima Daiichi nuclear power plant crisis, we propose a real-time, medical decision model by which to make key health-related decisions that are central drivers to the overall incident management.

Capacity of rat liver for pyrimidine synthesis and catabolism during fetal and neonatal development.

The capacity of minces of rat liver to synthesize and degrade pyrimidines during fetal and neonatal development was examined. Pyrimidine synthesis was determined by measuring the rate of incorporation of NaH14CO3 into orotic acid. Pyrimidine catabolism was estimated by measuring the generation of 14CO2 from [2-14C]uridine.

Isolation and immunochemical localization of collagenase in mouse peritoneal macrophages.

Collagenase was isolated from the culture medium of thioglycollate-stimulated mouse peritoneal exudate macrophages. The macrophage collagenase activity was inhibited by goat anti-mouse bone collagenase antibody, indicating that macrophage collagenase immunologically cross-reacts with mouse bone collagenase. The enzyme was localized in mouse peritoneal macrophages by indirect immunofluorescent antibody technique.