Objective: Recurrent pregnancy loss (RPL) has a multifactorial etiology, with a majority of cases remaining unexplained. To account for these unexplained cases, possible male factors are being explored. Conventional semen analysis lacks a qualitative assessment of sperms and information regarding sperm DNA integrity.
View Article and Find Full Text PDFBackground: Women with abnormal hysterosalpingography (HSG) are anxious regarding the presence of tubal pathology. It is important to know the predictive value of HSG and the need for subsequent laparoscopy following an abnormal report. In the era of assisted reproductive technology, the role of invasive testing such as diagnostic laparoscopy is being increasingly questioned due to its invasiveness and associated risks.
View Article and Find Full Text PDFThe prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%-17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
View Article and Find Full Text PDFBackground: Men with infertility experience significant distress, however research on psychiatric morbidity among this group is limited. Literature on explanatory models of infertility, which influence help seeking behaviour is also scarce.
Objectives: The aim of this cross-sectional study was to assess the prevalence and factors associated with psychiatric morbidity among men with infertility, their quality of life, and explanatory models regarding infertility.
Objective: To compare effectiveness of spontaneous ovulation monitored by urinary luteinising hormone (LH) versus induced ovulation by administration of human chorionic gonadotrophin (hCG) in couples undergoing gonadotrophin-stimulated intrauterine insemination (IUI).
Design: Randomised controlled trial.
Setting: University-level infertility unit.
Background: Assessment of ovarian reserve before an fertilization cycle (IVF) is one among the many factors that predicts a successful cycle. Individualized protocol based on ovarian reserve is designed to optimize the pregnancy outcome without compromising the patient safety. Although authors have shown that anti-Mullerian hormone-tailored (AMH) protocols have reduced the treatment burden and improved pregnancy rates, a few others have questioned its efficacy.
View Article and Find Full Text PDFObjectives: The overwhelming numbers of twins following assisted reproductive technology (ART) are dichorionic twins, but monochorionic twins account for around 0.9% of post ART pregnancies. The data for post ART-monochorionic pregnancy outcomes are scarce due to the rarity of this condition.
View Article and Find Full Text PDFJ Hum Reprod Sci
January 2013
Severe ovarian hyperstimulation syndrome remains one of the life threatening complication of assisted reproductive technology. In refractory cases of late ovarian hyperstimulation syndrome (OHSS), clinicians are left with limited therapeutic options. We report a case of refractory OHSS which was managed successfully using thawed plasma.
View Article and Find Full Text PDFObjectives: The literature regarding clinical outcomes following day 5/6 vitrified warmed blastocysts transfer has been conflicting. We decided to evaluate and compare the clinical outcomes following vitrified warmed day 5/6 blastocyst transfer using a solid surface vitrification protocol with fresh blastocyst transfers.
Settings: University teaching hospital.
Objective: The aim of the present study was to evaluate the prevalence of metabolic syndrome in women with polycystic ovary syndrome (PCOS).
Setting: Infertility clinic in a tertiary care hospital.
Study Design: A prospective cross-sectional study.
Objective: The objective was to evaluate the effectiveness of a blastocyst cryopreservation program using solid surface vitrification.
Setting: This study took place in a university teaching hospital.
Study Design: Retrospective observational study.
Background: Although ≈ 10% of the population is affected by infertility, the treatment option of in-vitro fertilisation (IVF) remains unaffordable for the majority of infertile couples. We have initiated a lowcost programme incorporating an uncommonly used, but recognized, ovarian stimulation protocol, together with certain costlimiting initiatives in an established assisted reproductive technology (ART) set up.
Methods: The medical records of women who underwent the lowcost programme were analysed.
Objective: To determine the predictive factors for pregnancy after controlled ovarian hyperstimulation (COH)/intrauterine insemination (IUI).
Design: Prospective observational study.
Setting: University-level tertiary care center.
In 36 women with polycystic ovary syndrome and clomiphene citrate resistance, letrozole, an aromatase inhibitor, statistically significantly increased the ovulation rate by 33.3% in the treatment group, indicating that letrozole can be used as an effective and simple alternate ovulation-inducing agent in these women.
View Article and Find Full Text PDFIsolated pleural effusion is a rare presentation of ovarian hyperstimulation syndrome. The pathogenesis of this disorder has not been fully elucidated. It supports the role of systemic factors rather than transudation of fluid from the surface of enlarged ovaries.
View Article and Find Full Text PDFObjective: To report a case of ovarian heterotopic pregnancy after an IVF cycle.
Design: Case report.
Setting: Reproductive medicine unit, Christian Medical College Hospital, Vellore, India.
Objective: Otogenic intracranial abscess complicating pregnancy has not been reported in world literature. We report the first case of cerebellar abscess secondary to chronic suppurative otitis media (CSOM) in a 23-year-old lady at 35 weeks of gestation. She was successfully treated by Caesarean section and delivery of a healthy baby, followed by combined neurosurgical and otologic procedures in the same anesthetic sitting.
View Article and Find Full Text PDFObjective: To evaluate the efficacy of blastocyst transfer in comparison with cleavage stage embryo in a similar cohort of women.
Design: Retrospective analysis.
Setting: University teaching hospital.
Antenatal prevalence is more than 1% in parts of India, yet little is known about the complications and fetal outcomes in this region. We reviewed the records of 23,386 women who delivered at the Christian Medical College Hospital in Vellore, India from 2000 through 2002. HIV-infected women were more likely than HIV-uninfected women to have pregnancy-induced hypertension, anaemia, breech presentations, stillborn babies and fetal deaths.
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