Publications by Alexy Schulga

Publications by authors named "Alexy Schulga"

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Structural features of Cas2 from Thermococcus onnurineus in CRISPR-cas system type IV.

Tae-Yang Jung Kwang-Hyun Park Yan An Alexy Schulga Sergey Deyev

Protein Sci

October 2016

CRISPR-Cas is RNA-based prokaryotic immune systems that defend against exogenous genetic elements such as plasmids and viruses. Cas1 and Cas2 are highly conserved components that play an essential part in the adaptation stage of all CRISPR-Cas systems. Characterization of CRISPR-Cas genes in Thermococcus onnurineus reveals the association of the Cas2 gene with the putative type IV system that lacks Cas1 or its homologous genes.

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