Publications by authors named "Alexis de Haven-Brandon"
Page 2 of 1
Synopsis of recent research by authors named "Alexis de Haven-Brandon"
Recent research by Alexis de Haven-Brandon primarily focuses on developing and optimizing small molecules for targeting critical pathways in various cancers, particularly those driven by oncogenic factors such as BCL6 and MYCN.!
Key findings include the discovery of enhanced chemical probes for inhibiting BCL6, a driver of diffuse large B-cell lymphoma, and demonstrating the therapeutic potential of CDK9/2 inhibitors in MYCN-driven neuroblastoma, highlighting novel mechanisms of action against these cancers.!
Additionally, the research explores the role of fibroblast growth factor signaling in rhabdomyosarcoma and the identification of estrogen-sensitive ovarian cancer models, contributing to a broader understanding of treatment challenges and opportunities in pediatric and ovarian cancers.!
