The effect of anastrazole on symptomatic uterine leiomyomata.

Objective: To evaluate the effect of anastrazole on symptomatic uterine leiomyomata.

Methods: This was a prospective intervention study carried out in a university department of obstetrics and gynecology. Forty-one premenopausal women eligible for hysterectomy with 45 uterine leiomyomata were enrolled and treated with anastrazole 1 mg daily for three cycles of 28 days each.

Homocysteine, folic acid and B12 serum levels in pregnancy complicated with preeclampsia.

Objective: Elevated plasma homocysteine has been implicated in vascular changes compatible with atherosis and endothelial dysfunction similar to the vascular changes of the placenta in preeclampsia. Previous reports have indicated an increased incidence of hyperohomocysteinemia in preeclamptic patients. The aim of this study was to examine the association of homocysteine levels and preeclampsia in our patients.