Publications by authors named "Alexis K de Haven Brandon"
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Synopsis of recent research by authors named "Alexis K de Haven Brandon"
- Alexis K De Haven Brandon's research primarily focuses on the design and optimization of small molecule inhibitors targeting key regulatory proteins involved in cancer, such as BCL6 and CHK1, with an emphasis on improving their pharmacokinetic properties and cellular efficacy.
- Recent publications detail the advancement of innovative chemical probes, notably the identification of potent BCL6 inhibitors and orally active CHK1 inhibitors, demonstrating their potential for sustained therapeutic action against various lymphoid malignancies and solid tumors.
- The research also highlights the application of advanced drug discovery technologies and modeling approaches to characterize the pharmacodynamic effects of these inhibitors in preclinical settings, aiming to enhance the effectiveness and selectivity of cancer therapies.
