Development and Validation of a Novel Mobility Test for Rod-Cone Dystrophies: From Reality to Virtual Reality.

Purpose: To validate a novel mobility test (MOST, MObility Standardized Test) and performance outcomes in real (RL) and virtual (VR) environments to be used for interventional clinical studies in order to characterize vision impairment in rod-cone dystrophies, also known as retinitis pigmentosa (RP).

Design: Prospective, interventional, noninvasive, reliability and validity analysis.

Methods: We designed MOST to be used in both VR and RL and conducted 3 experimental studies with 89 participants to (1) validate the difficulty of the mobility courses (15 controls), (2) determine the optimal number of light levels and training trials (14 participants with RP), and (3) validate the reproducibility (test-retest), reliability (VR/RL), sensitivity, and construct/content validity of the test (30 participants with RP and 30 controls).

Availability of attention affects time-to-contact estimation.

To estimate the time-to-contact (TTC) of a moving object, numerous studies have focused on the type of information or gaze strategy used by the observer. However, it remains to be determined whether and how attention could affect TTC estimation. In particular, how does TTC estimation operate when less attention is available? To answer this question, we conducted two experiments in which the participants had to perform an absolute (Experiment 1) or relative (Experiment 2) prediction-motion task, either alone (i.

Dual-task automatization: The key role of sensory-motor modality compatibility.

How do people automatize their dual-task performance through bottleneck bypassing (i.e., accomplish parallel processing of the central stages of two tasks)? In the present work we addressed this question, evaluating the impact of sensory-motor modality compatibility-the similarity in modality between the stimulus and the consequences of the response.