Publications by authors named "Alexis De Haven Brandon"
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Synopsis of recent research by authors named "Alexis De Haven Brandon"
Alexis De Haven Brandon's research primarily focuses on the development of small-molecule inhibitors and degraders targeting oncogenic drivers in various cancers, including diffuse large B-cell lymphoma and neuroblastoma.
Recent findings highlight the optimization of compounds such as tricyclic quinolinones and benzimidazolones that effectively inhibit the BCL6 transcriptional repressor, which is critical in lymphoid malignancies.
Additionally, the investigations into rhabdomyosarcoma and multiple myeloma emphasize novel therapeutic strategies involving FGFR targeting and combined MEK and glucocorticoid receptor inhibition, pointing to the promise of enhanced treatment options for challenging cancer types.
