Publications by authors named "Alexis Davison"
Modulatory neurotransmitters exert powerful control over neurons and the brain vasculature. Gamma Entrainment Using Sensory Stimuli (GENUS) promotes amyloid clearance via increased perivascular cerebral spinal fluid (CSF) flux in mouse models of Alzheimer's Disease. Here we use whole-brain activity mapping to identify the cholinergic basal forebrain as a key region responding to GENUS.
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- - Demyelination involves the loss of myelin sheath and oligodendrocytes, leading to damaged axons, brain atrophy, and neuronal degeneration due to neuroinflammation and cell death.
- - The study uses a cuprizone mouse model to explore the effects of non-invasive gamma stimulation through sensory input as a treatment method for promoting myelination and reducing inflammation.
- - Results indicate that multisensory gamma stimulation can reduce demyelination, promote the formation of oligodendrocytes, maintain neuronal function, and lessen brain inflammation, highlighting its potential as a therapy for demyelinating diseases.