Publications by authors named "Alexis Coulis"

Article Synopsis
  • - Cardiopulmonary exercise testing helps understand why people with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension struggle with exercise.
  • - Different underlying health issues can influence how we interpret symptoms like shortness of breath, tired legs, and overall difficulty with exercise.
  • - This testing provides a detailed look at how these diseases affect people's physical performance and overall quality of life.
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Purpose: This study aims to review the published literature concerning the use of novel oral anticoagulants (NOACs) in the treatment and prevention of venous thromboembolism (VTE) and to identify the appropriate niche for each NOAC by comparing their behaviors in Phase III and Phase IV clinical trial settings.

Methods: The ClinicalTrials.gov database was used to identify Phase III and postmarketing (Phase IV) randomized controlled trials concerning the efficacy and safety profiles of the oral NOACs (apixaban, dabigatran etexilate, exodaban, and rivaroxaban) for the treatment or prevention of VTE.

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