A case report of bladder leiomyoma: an unusual bladder tumour.

Leiomyomas are benign mesenchymal tumours that rarely arise in the bladder. We present a case of a 53-year-old female who was incidentally diagnosed with a bladder leiomyoma identified on CT imaging performed for investigation of a urachal remnant. We discuss the investigation and management of this lesion in the context of modern urology practice.

Spontaneous rupture of continent urinary reservoir with extrophy-epispadias complex.

Spontaneous rupture of a continent urinary reservoir is a rare, but clinically important event. The diagnosis of reservoir rupture should be considered in any patient with peritonitis and a history of continent urinary diversion. A pouchogram may confirm the diagnosis, but ultimately a laparotomy is mandatory in the setting of peritonitis and sepsis.

Molecular pathways in prostate cancer.

Objectives: Prostate cancer is a prevalent disease with a high impact on patients' morbidity and mortality. Despite efforts to profile prostate cancer, the genetic alterations and biological processes that correlate with disease progression remain partially elusive. The purpose of this study is to review the recent evidence relating to the initiation and progression of prostate cancer in relation to the familial correlation of the disease, the genetic aberrations resulting in prostate cancer and the new molecular biology data regarding prostate cancer.