Publications by authors named "Alexia N Pearah"
Infect Immun
October 2024
Article Synopsis
- Group B Streptococcus (GBS) is a major cause of neonatal sepsis, particularly because vulnerable newborns have underdeveloped intestinal barriers that allow GBS to invade.
- The study investigates the effects of butyrate, a fatty acid produced from dietary fiber fermentation, on GBS-induced damage to intestinal barriers and shows that butyrate reduces cell death and enhances barrier function.
- Maternal butyrate treatment in mice also leads to lower GBS levels in offspring, highlighting its potential as a preventive strategy against neonatal sepsis amid growing concerns of antibiotic resistance.
